NAPRT1 (NAPRT) (NM_145201) Human Recombinant Protein
CAT#: TP760543
Purified recombinant protein of Human nicotinate phosphoribosyltransferase domain containing 1 (NAPRT1), with N-terminal HIS tag, expressed in E.Coli, 50ug
View other "NAPRT1" proteins (2)
Need it in bulk or customized? Get a free quote |
CNY 2,040.00
货期*
2周
规格
Cited in 2 publications. |
经常一起买 (1)
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length NAPRT1
|
Tag | N-His |
Predicted MW | 49.4 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50 mM Tris-HCl, pH 8.0, 8 M urea |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_660202 |
Locus ID | 93100 |
UniProt ID | Q6XQN6 |
Refseq Size | 1875 |
Cytogenetics | 8q24.3 |
Refseq ORF | 1398 |
Synonyms | NAPRT1; PP3856 |
Summary | Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).[supplied by OMIM, Mar 2008] |
Citations (2)
The use of this Proteins has been cited in the following citations: |
---|
Novel NAPRT specific antibody identifies small cell lung cancer and neuronal cancers as promising clinical indications for a NAMPT inhibitor/niacin co-administration strategy
,null,
Oncotarget
,PubMed ID 29100430
[NAPRT]
|
Loss of NAPRT1 expression by tumor-specific promoter methylation provides a novel predictive biomarker for NAMPT inhibitors.
,null,
Clinical cancer research : an official journal of the American Association for Cancer Research
,PubMed ID 24097869
[NAPRT]
|
Documents
FAQs |
SDS |
Resources
蛋白相关资源 |
Customer
Reviews
Loading...