MSL2L1 (MSL2) (NM_018133) Human Recombinant Protein
CAT#: TP760587
Purified recombinant protein of Human male-specific lethal 2 homolog (Drosophila) (MSL2), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
View other "MSL2L1" proteins (4)
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CNY 2,040.00
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length MSL2
|
Tag | N-His |
Predicted MW | 62.4 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50 mM Tris-HCl, pH 8.0, 8 M urea |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_060603 |
Locus ID | 55167 |
UniProt ID | Q9HCI7 |
Refseq Size | 4696 |
Cytogenetics | 3q22.3 |
Refseq ORF | 1731 |
Synonyms | MSL-2; MSL2L1; RNF184 |
Summary | Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at 'Lys-35' (H2BK34Ub), but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histine H3 methylation at 'Lys-4' (H3K4me) and 'Lys-79' (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1.[UniProtKB/Swiss-Prot Function] |
Protein Families | Druggable Genome |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC413286 | MSL2 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LC428876 | MSL2 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LY413286 | Transient overexpression lysate of male-specific lethal 2 homolog (Drosophila) (MSL2), transcript variant 1 |
CNY 3,080.00 |
|
LY428876 | Transient overexpression lysate of male-specific lethal 2 homolog (Drosophila) (MSL2), transcript variant 2 |
CNY 3,080.00 |