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MYH (MUTYH) (NM_012222) Human Recombinant Protein
CAT＃: TP760878
Purified recombinant protein of Human mutY homolog (E. coli) (MUTYH / MYH), transcript variant alpha1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
View other "MYH" proteins (12)
|
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CNY 2,040.00
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Specifications
| Product Data | |
| Species | Human |
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length MUTYH
|
| Tag | N-His |
| Predicted MW | 59.9 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Reference Data | |
| RefSeq | NP_036354 |
| Locus ID | 4595 |
| UniProt ID | Q9UIF7 |
| Refseq Size | 1854 |
| Cytogenetics | 1p34.1 |
| Refseq ORF | 1638 |
| Synonyms | MYH |
| Summary | This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. This gene product is thought to play a role in signaling apoptosis by the introduction of single-strand breaks following oxidative damage. Mutations in this gene result in heritable predisposition to colorectal cancer, termed MUTYH-associated polyposis (MAP). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2017] |
| Protein Families | Druggable Genome, Stem cell - Pluripotency |
| Protein Pathways | Base excision repair |
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| 蛋白相关资源 |
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC420769 | MUTYH HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
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| LC420770 | MUTYH HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
| LC420771 | MUTYH HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC425817 | MUTYH HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC426953 | MUTYH HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY420769 | Transient overexpression lysate of mutY homolog (E. coli) (MUTYH), transcript variant gamma2 |
CNY 4,840.00 |
|
| LY420770 | Transient overexpression lysate of mutY homolog (E. coli) (MUTYH), transcript variant gamma3 |
CNY 4,840.00 |
|
| LY420771 | Transient overexpression lysate of mutY homolog (E. coli) (MUTYH), transcript variant beta3 |
CNY 3,080.00 |
|
| LY425817 | Transient overexpression lysate of mutY homolog (E. coli) (MUTYH), transcript variant gamma3 |
CNY 3,080.00 |
|
| LY426953 | Transient overexpression lysate of mutY homolog (E. coli) (MUTYH), transcript variant alpha5 |
CNY 3,080.00 |
|
| TP761664 | Purified recombinant protein of Human mutY homolog (E. coli) (MUTYH), transcript variant beta3, full length, with N-terminal HIS tag, expressed in E. coli, 50ug |
CNY 2,040.00 |
|
| TP761725 | Purified recombinant protein of Human mutY homolog (E. coli) (MUTYH), transcript variant gamma3, full length, with N-terminal His tag, expressed in E. coli, 50ug |
CNY 2,040.00 |
