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NF2 (NM_181831) Human Recombinant Protein
CAT＃: TP761274
Purified recombinant protein of Human neurofibromin 2 (merlin) (NF2), transcript variant 13, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
View other "NF2" proteins (10)
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CNY 2,040.00
| Cited in 1 publication. |
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Specifications
| Product Data | |
| Species | Human |
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length NF2
|
| Tag | N-His |
| Predicted MW | 58.9 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 50 mM Tris-HCl, pH 8.0, 8 M urea |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Reference Data | |
| RefSeq | NP_861969 |
| Locus ID | 4771 |
| UniProt ID | P35240 |
| Refseq Size | 2217 |
| Cytogenetics | 22q12.2 |
| Refseq ORF | 1521 |
| Synonyms | ACN; BANF; merlin-1; SCH |
| Summary | This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts. [provided by RefSeq, Jul 2008] |
| Protein Families | Druggable Genome |
Citations (1)
| The use of this Proteins has been cited in the following citations: |
|---|
|
Missense mutations in the NF2 gene result in the quantitative loss of merlin protein and minimally affect protein intrinsic function
,null,
Proceedings of the National Academy of Sciences of the United States of America
,PubMed ID 21383154
[NF2]
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| 蛋白相关资源 |
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC400101 | NF2 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC405605 | NF2 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC405606 | NF2 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
| LC405607 | NF2 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
| LC430575 | NF2 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY400101 | Transient overexpression lysate of neurofibromin 2 (merlin) (NF2), transcript variant 1 |
CNY 3,080.00 |
|
| LY405605 | Transient overexpression lysate of neurofibromin 2 (merlin) (NF2), transcript variant 7 |
CNY 3,080.00 |
|
| LY405606 | Transient overexpression lysate of neurofibromin 2 (merlin) (NF2), transcript variant 13 |
CNY 4,840.00 |
|
| LY405607 | Transient overexpression lysate of neurofibromin 2 (merlin) (NF2), transcript variant 8 |
CNY 4,840.00 |
|
| LY430575 | Transient overexpression lysate of neurofibromin 2 (merlin) (NF2), transcript variant 13 |
CNY 3,080.00 |
