ELL (NM_006532) Human Recombinant Protein
CAT#: TP761317
Purified recombinant protein of Human elongation factor RNA polymerase II (ELL), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
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CNY 2,040.00
货期*
现货
规格
经常一起买 (1)
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Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length ELL
|
Tag | N-GST and C-His |
Predicted MW | 94.1 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_006523 |
Locus ID | 8178 |
UniProt ID | P55199 |
Refseq Size | 4077 |
Cytogenetics | 19p13.11 |
Refseq ORF | 1863 |
Synonyms | C19orf17; ELL1; MEN; PPP1R68 |
Summary | Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Elongation factor component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968, PubMed:23932780). Specifically required for stimulating the elongation step of RNA polymerase II- and III-dependent snRNA gene transcription (PubMed:23932780). ELL also plays an early role before its assembly into in the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site. Required to stabilize the pre-initiation complex and early elongation.[UniProtKB/Swiss-Prot Function] |
Protein Families | Transcription Factors |
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