p95 NBS1 (NBN) (NM_002485) Human Recombinant Protein

CAT#: TP762026

Purified recombinant protein of Human nibrin (NBN),Pro461-Arg754, with N-terminal His tag, expressed in E. coli, 50ug



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CNY 2,050.00


货期*
现货

规格
    • 50 ug

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经常一起买 (1)
NBN mouse monoclonal antibody,clone OTI6E11
    • 100 ul

CNY 1,999.00
CNY 2,700.00

Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region(Pro461-Arg754) of NBN
Tag N-His
Predicted MW 34 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_002476
Locus ID 4683
UniProt ID O60934
Refseq Size 4639
Cytogenetics 8q21.3
Refseq ORF 2262
Synonyms AT-V1; AT-V2; ATV; NBS; NBS1; P95
Summary Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways Homologous recombination
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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