p95 NBS1 (NBN) (NM_002485) Human Recombinant Protein
CAT#: TP762026
Purified recombinant protein of Human nibrin (NBN),Pro461-Arg754, with N-terminal His tag, expressed in E. coli, 50ug
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CNY 2,050.00
货期*
现货
规格
经常一起买 (1)
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CNY 1,999.00
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Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding the region(Pro461-Arg754) of NBN
|
Tag | N-His |
Predicted MW | 34 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_002476 |
Locus ID | 4683 |
UniProt ID | O60934 |
Refseq Size | 4639 |
Cytogenetics | 8q21.3 |
Refseq ORF | 2262 |
Synonyms | AT-V1; AT-V2; ATV; NBS; NBS1; P95 |
Summary | Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome |
Protein Pathways | Homologous recombination |
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