DKK1 (NM_012242) Human Recombinant Protein
CAT#: TP762060
Purified recombinant protein of Human dickkopf homolog 1 (Xenopus laevis) (DKK1),Thr32-End, with N-terminal His tag, expressed in E. coli, 50ug
View other "DKK1" proteins (3)
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CNY 2,050.00
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding the region(Thr32-End) of DKK1
|
Tag | N-His |
Predicted MW | 25.8 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50 mM Tris-HCl, pH 8.0, 8 M urea |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_036374 |
Locus ID | 22943 |
UniProt ID | O94907, I1W660 |
Refseq Size | 1815 |
Cytogenetics | 10q21.1 |
Refseq ORF | 798 |
Synonyms | DKK-1; SK |
Summary | This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The encoded protein binds to the LRP6 co-receptor and inhibits beta-catenin-dependent Wnt signaling. This gene plays a role in embryonic development and may be important in bone formation in adults. Elevated expression of this gene has been observed in numerous human cancers and this protein may promote proliferation, invasion and growth in cancer cell lines. [provided by RefSeq, Sep 2017] |
Protein Families | Adult stem cells, Cancer stem cells, Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Stem cell relevant signaling - Wnt Signaling pathway |
Protein Pathways | Wnt signaling pathway |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC402176 | DKK1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LY402176 | Transient overexpression lysate of dickkopf homolog 1 (Xenopus laevis) (DKK1) |
CNY 3,080.00 |
|
TP710289 | Purified recombinant protein of Human dickkopf homolog 1 (Xenopus laevis) (DKK1), full length, with C-terminal DDK tag, expressed in sf9, 20ug |
CNY 4,020.00 |