United States
Germany
Japan
United Kingdom
China
NRG1 (NM_013956) Human Recombinant Protein
CAT＃: TP762321
Purified recombinant protein of Human neuregulin 1 (NRG1), transcript variant HRG-beta1, Ser20-Glu242, with N-terminal His tag, expressed in E.coli, 50ug
View other "NRG1" proteins (17)
|
Need it in bulk or customized? Get a free quote |
CNY 1,950.00
| Cited in 2 publications. |
Product images
CNY 1,999.00
CNY 3,600.00
Specifications
| Product Data | |
| Species | Human |
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence |
A DNA sequence encoding the region(Ser20-Glu242) of NRG1
|
| Tag | N-His |
| Predicted MW | 24.2 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 50 mM Tris-HCl, pH 8.0, 8 M urea |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C after receiving vials. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Reference Data | |
| RefSeq | NP_039250 |
| Locus ID | 3084 |
| UniProt ID | Q02297 |
| Refseq Size | 2583 |
| Cytogenetics | 8p12 |
| Refseq ORF | 1935 |
| Synonyms | ARIA; GGF; GGF2; HGL; HRG; HRG1; HRGA; MST131; MSTP131; NDF; NRG1-IT2; SMDF |
| Summary | The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). [provided by RefSeq, Apr 2016] |
| Protein Families | Druggable Genome, Secreted Protein, Transcription Factors, Transmembrane |
| Protein Pathways | ErbB signaling pathway |
Citations (2)
| The use of this Proteins has been cited in the following citations: |
|---|
|
Identification of candidate genes for congenital heart defects on proximal chromosome 8p
,null,
Scientific Reports
,PubMed ID 27808268
[NRG1]
|
|
The anti-HER3 antibody patritumab abrogates cetuximab resistance mediated by heregulin in colorectal cancer cells
,null,
Oncotarget
,PubMed ID 25474137
[NRG1]
|
Documents
| FAQs |
| SDS |
Resources
| 蛋白相关资源 |
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC415553 | NRG1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
| LC415555 | NRG1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC415558 | NRG1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC415560 | NRG1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
| LC431269 | NRG1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC431507 | NRG1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC431526 | NRG1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY415553 | Transient overexpression lysate of neuregulin 1 (NRG1), transcript variant HRG-beta1 |
CNY 4,840.00 |
|
| LY415555 | Transient overexpression lysate of neuregulin 1 (NRG1), transcript variant HRG-beta3 |
CNY 3,080.00 |
|
| LY415558 | Transient overexpression lysate of neuregulin 1 (NRG1), transcript variant GGF |
CNY 3,080.00 |
|
| LY415560 | Transient overexpression lysate of neuregulin 1 (NRG1), transcript variant HRG-alpha |
CNY 4,840.00 |
|
| LY431269 | Transient overexpression lysate of neuregulin 1 (NRG1), transcript variant ndf43c |
CNY 3,080.00 |
|
| LY431507 | Transient overexpression lysate of neuregulin 1 (NRG1), transcript variant HRG-beta1d |
CNY 3,080.00 |
|
| LY431526 | Transient overexpression lysate of neuregulin 1 (NRG1), transcript variant HRG-beta1c |
CNY 3,080.00 |
|
| TP721214 | Purified recombinant protein of Human neuregulin 1 (NRG1), transcript variant GGF2 |
CNY 1,800.00 |
|
| TP721215 | Purified recombinant protein of Human neuregulin 1 (NRG1), transcript variant GGF2 |
CNY 1,800.00 |
|
| TP762500 | Purified recombinant protein of Human neuregulin 1 (NRG1), transcript variant HRG-alpha, 20Ser-230Gln, with N-terminal His tag, expressed in E.coli, 50ug |
CNY 2,150.00 |
