ABCB4 (NM_018849) Human Recombinant Protein

CAT#: TP762713

Purified recombinant protein of Human ATP-binding cassette, sub-family B (MDR/TAP), member 4 (ABCB4), transcript variant B, 1Met-60Gly GlyGlyGlyGlySer 600Ile-700Val, with N-terminal His tag, expressed in E.coli, 50ug



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CNY 2,480.00


货期*
现货

规格
    • 50 ug

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经常一起买 (1)
Rabbit Polyclonal Anti-ABCB4 Antibody
    • 100 ul

CNY 5,250.00

Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region (1Met-60Gly GlyGlyGlyGlySer 600Ile-700Val) of ABCB4
Tag N-His
Predicted MW 20.7 kDa
Concentration >0.05 ug/ul as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25mM Tris, 150mM NaCl, 10% glycerol, pH8.0, 1% SKL
Storage Store at -80°C after receiving vials.
Stability Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_061337
Locus ID 5244
UniProt ID P21439
Refseq Size 3988
Cytogenetics 7q21.12
Refseq ORF 3858
Synonyms ABC21; GBD1; ICP3; MDR2; MDR2/3; MDR3; PFIC-3; PGY3
Summary The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Transmembrane
Protein Pathways ABC transporters
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