MIR21 Human MicroRNA Expression Plasmid (MI0000077)

CAT＃: SC400271

Expression plasmid for human microRNA MIR21

Datasheet
SDS

CNY 3,420.00

货期*
现货
规格
    • 10 ug
Cited in 12 publications.

Product images

经常一起买 (1)
CC100003
DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00

暂停销售

Specifications

Product Data
Species Human
Vector pCMV-MIR
Sequence Data
Precursor:
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACACCAGUCGAUGGGCUGUCUGACA
Mature Sequence:
UAGCUUAUCAGACUGAUGUUGA
>MI0000077 CAGTTTTCTTGCCGTTCTGTAAGTGTTTTATTCTTAGTGTGATTTTTTTCCATTGGGATGTTTTTGATTG
AACTTGTTCATTTTGTTTTGCTTGGGAGGAAAATAAACAATTTTACTTTTTTCCTTTAGGAGCATTATGA
GCATTATGTCAGAATAGAATAGAATTGGGGTTCGATCTTAACAGGCCAGAAATGCCTGGGTTTTTTTGGT
TTGTTTTTGTTTTTGTTTTTTTATCAAATCCTGCCTGACTGTCTGCTTGTTTTGCCTACCATCGTGACAT
CTCCATGGCTGTACCACCTTGTCGGGTAGCTTATCAGACTGATGTTGACTGTTGAATCTCATGGCAACAC
CAGTCGATGGGCTGTCTGACATTTTGGTATCTTTCATCTGACCATCCATATCCAATGTTCTCATTTAAAC
ATTACCCAGCATCATTGTTTATAATCAGAAACTCTGGTCCTTCTGTCTGGTGGCACTTAGAGTCTTTTGT
GCCATAATGCAGCAGTATGGAGGGAGGATTTTATGGAGAAATGGGGATAGTCTTCATGACCACAAATAAA
TAAAGGAAAACTAAGCTGCATTGTGGGTTTTGAAAAGGTTATTATACTTCTTAACAATTCTTTTTTTCAG
GGACTTTTCTAGCTGTATGAC
OTI Disclaimer All miRNA clones were sequenced to ensure that the pre-mir sequences match reference sequence in miRBase. The flanking sequence of a miRNA clone may differ from the NCBI reference with respect to biological polymorphisms. This should not affect the function of the mature miRNA.
Product Components 1 x 10 ug vial miRNA plasmid lyophilized in a 2-D bar-coded Matrix tube
Also Contains Both mature and minor (star) miRNA can be over expressed from the construct.
Reference Data
RefSeq MI0000077
Synonyms MIRN21 miR-21 miRNA21 hsa-mir-21
Locus ID 406991
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (12)

The use of this RNAi has been cited in the following citations:
The Interaction of Influenza A NS1 and Cellular TRBP Protein Modulates the Function of RNA Interference Machinery ,null, Frontiers in Microbiology ,PubMed ID 35558132 [MIR21]
Overexpression of miR-21-5p in colorectal cancer cells promotes self-assembly of E-cadherin-dependent multicellular tumor spheroids ,Li, A;Yang, P;, Tissue and Cell [MIR21]
In Vitro and In Silico Mechanistic Insights into miR-21-5p-Mediated Topoisomerase Drug Resistance in Human Colorectal Cancer Cells ,Chen, JC;Hsieh, YY;Lo, HL;Li, A;Chou, CJ;Yang, PM;, Biomolecules ,PubMed ID 31505885 [MIR21]
TLR4/ROS/miRNA-21 pathway underlies lipopolysaccharide instructed primary tumor outgrowth in lung cancer patients ,Zhang, X;Wang, C;Shan, S;Liu, X;Jiang, Z;Ren, T;, Oncotarget ,PubMed ID 27286259 [MIR21]
Targeting miR-21-3p inhibits proliferation and invasion of ovarian cancer cells ,Báez-Vega, PM;Echevarría Vargas, IM;Valiyeva, F;Encarnación-Rosado, J;Roman, A;Flores, J;Marcos-Martínez, MJ;Vivas-Mejía, PE;, Oncotarget ,PubMed ID 27166999 [MIR21]
Extracellular miRNA-21 as a novel biomarker in glioma: Evidence from meta-analysis, clinical validation and experimental investigations ,Qu, K;Lin, T;Pang, Q;Liu, T;Wang, Z;Tai, M;Meng, F;Zhang, J;Wan, Y;Mao, P;Dong, X;Liu, C;Niu, W;Dong, S;, Oncotarget ,PubMed ID 27166186 [MIR21]
Glyoxalase I drives epithelial-to-mesenchymal transition via argpyrimidine-modified Hsp70, miR-21 and SMAD signalling in human bronchial cells BEAS-2B chronically exposed to crystalline silica Min-U-Sil 5: Transformation into a neoplastic-like phenotype ,Antognelli, C;Gambelunghe, A;Muzi, G;Talesa, VN;, Free Radic. Biol. Med. ,PubMed ID 26784015 [MIR21]
Hypomethylation of miR-142 promoter and upregulation of microRNAs that target the oxytocin receptor gene in the autism prefrontal cortex ,Mor, M;Nardone, S;Sams, DS;Elliott, E;, Mol Autism ,PubMed ID 26273428 [MIR21]
MicroRNA-21 Promotes Cell Growth and Migration by Targeting Programmed Cell Death 4 Gene in Kazakh's Esophageal Squamous Cell Carcinoma ,Liu, T;Liu, Q;Zheng, S;Gao, X;Lu, M;Yang, C;Dai, F;, Disease Markers [MIR21]
MiRNA-21/DDAH1 pathway regulates pulmonary vascular responses to hypoxia ,Iannone, L;Zhao, L;Dubois, O;Duluc, L;Rhodes, CJ;Wharton, J;Wilkins, MR;Leiper, J;Wojciak-Stothard, B;, Biochem. J. ,PubMed ID 24895913 [MIR21]
Upregulation of miR-21 in Cisplatin Resistant Ovarian Cancer via JNK-1/c-Jun Pathway ,Echevarría-Vargas, IM;Valiyeva, F;Vivas-Mejía, PE;, PLoS ONE ,PubMed ID 24865582 [MIR21]
MicroRNA-21 induces stemness by downregulating transforming growth factor beta receptor 2 (TGFßR2) in colon cancer cells ,Yingjie Yu, Shailender S. Kanwar, Bhaumik B. Patel, Phil-Sun Oh, Jyoti Nautiyal, Fazlul H. Sarkar, and Adhip P.N. Majumdar, Carcinogenesis, Jan 2012; 33: 68 - 76. [mir21]

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