GPR120 (FFAR4) Human shRNA Plasmid Kit (Locus ID 338557)
CAT#: TF307824
GPR120 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
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CNY 4,790.00
货期*
现货
规格
Cited in 4 publications. |
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经常一起买 (2)
Specifications
Product Data | |
Product Name | GPR120 (FFAR4) Human shRNA Plasmid Kit (Locus ID 338557) |
Locus ID | 338557 |
UniProt ID | Q5NUL3 |
Synonyms | BMIQ10; GPR120; GPR129; GT01; O3FAR1; PGR4 |
Vector | pRFP-C-RS |
Format | Retroviral plasmids |
Kit Components | GPR120 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 338557). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
RefSeq | NM_001195755, NM_181745, NM_181745.1, NM_181745.2, NM_181745.3, NM_001195755.1, BC101175, BM757151, NM_001195755.2, NM_181745.4 |
Summary | This gene encodes a G protein-coupled receptor (GPR) which belongs to the rhodopsin family of GPRs. The encoded protein functions as a receptor for free fatty acids, including omega-3, and participates in suppressing anti-inflammatory responses and insulin sensitizing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012] |
shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
Performance Guaranteed | OriGene guarantees that the sequences in the shRNA expression cassettes are verified to correspond to the target gene with 100% identity. One of the four constructs at minimum are guaranteed to produce 70% or more gene expression knock-down provided a minimum transfection efficiency of 80% is achieved. Western Blot data is recommended over qPCR to evaluate the silencing effect of the shRNA constructs 72 hrs post transfection. To properly assess knockdown, the gene expression level from the included scramble control vector must be used in comparison with the target-specific shRNA transfected samples. For non-conforming shRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the shRNA kit. To arrange for a free replacement with newly designed constructs, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled shRNA control (Western Blot data preferred). |
Citations (4)
The use of this RNAi has been cited in the following citations: |
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Regulation of cell survival through free fatty acid receptor 1 (FFA1) and FFA4 induced by endothelial cells in osteosarcoma cells
,Minami, K;Ueda, N;Ishimoto, K;Tsujiuchi, T;,
J. Recept. Signal Transduct. Res.
,PubMed ID 32026734
[FFAR4]
|
Involvement of FFA1 and FFA4 in the regulation of cellular functions during tumor progression in colon cancer cells
,Takahashi, K;Fukushima, K;Onishi, Y;Minami, K;Otagaki, S;Ishimoto, K;Fukushima, N;Honoki, K;Tsujiuchi, T;,
Exp. Cell Res.
,PubMed ID 29750897
[FFAR4]
|
Different effects of GPR120 and GPR40 on cellular functions stimulated by 12-O-tetradecanoylphorbol-13-acetate in melanoma cells
,Fukushima, K;Takahashi, K;Fukushima, N;Honoki, K;Tsujiuchi, T;,
Biochem. Biophys. Res. Commun.
,PubMed ID 27163640
[FFAR4]
|
Different roles of GPR120 and GPR40 in the acquisition of malignant properties in pancreatic cancer cells
,Fukushima, K;Yamasaki, E;Ishii, S;Tomimatsu, A;Takahashi, K;Hirane, M;Fukushima, N;Honoki, K;Tsujiuchi, T;,
Biochem. Biophys. Res. Commun.
,PubMed ID 26282200
[FFAR4]
|
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