CPNE1 Human shRNA Plasmid Kit (Locus ID 8904)

Specifications

Product Data
Product Name	CPNE1 Human shRNA Plasmid Kit (Locus ID 8904)
Locus ID	8904
UniProt ID	Q99829
Synonyms	COPN1; CPN1
Vector	pGFP-C-shLenti
Format	Lentiviral plasmids
Kit Components	CPNE1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 8904). 5µg purified plasmid DNA per construct 29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq	NM_001198863, NM_003915, NM_152925, NM_152926, NM_152927, NM_152928, NM_152929, NM_152930, NM_152931, NR_037188, NM_152928.1, NM_152928.2, NM_152925.1, NM_152925.2, NM_152926.1, NM_152926.2, NM_003915.1, NM_003915.2, NM_003915.3, NM_003915.5, NM_152927.1, NM_152927.2, NM_001198863.1, NM_152930.1, NM_152931.1, NM_152929.1, BC001142, BC001142.1, BC021010, BM755522, NM_001198863.2, NM_152926.3, NM_152925.3, NM_152927.3, NM_152928.3
Summary	Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene encodes a calcium-dependent protein that also contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, the encoded protein does not contain a predicted signal sequence or transmembrane domains. This protein has a broad tissue distribution and it may function in membrane trafficking. This gene and the gene for RNA binding motif protein 12 overlap at map location 20q11.21. Alternate splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Aug 2008]
shRNA Design	These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Performance Guaranteed	OriGene guarantees that the sequences in the shRNA expression cassettes are verified to correspond to the target gene with 100% identity. One of the four constructs at minimum are guaranteed to produce 70% or more gene expression knock-down provided a minimum transfection efficiency of 80% is achieved. Western Blot data is recommended over qPCR to evaluate the silencing effect of the shRNA constructs 72 hrs post transfection. To properly assess knockdown, the gene expression level from the included scramble control vector must be used in comparison with the target-specific shRNA transfected samples. For non-conforming shRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the shRNA kit. To arrange for a free replacement with newly designed constructs, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled shRNA control (Western Blot data preferred).

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.