Cltc Mouse shRNA Plasmid (Locus ID 67300)
CAT#: TL516542
Cltc - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
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CNY 5,740.00
货期*
现货
规格
Cited in 1 publication. |
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经常一起买 (3)
Specifications
Product Data | |
Product Name | Cltc Mouse shRNA Plasmid (Locus ID 67300) |
Locus ID | 67300 |
UniProt ID | Q68FD5 |
Synonyms | 3110065L21Rik; CHC; R74732 |
Vector | pGFP-C-shLenti |
Format | Lentiviral plasmids |
Kit Components | Cltc - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 67300). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
RefSeq | BC079897, NM_001003908, NM_001356393, NM_001003908.1, BC031408, BC035544, NM_001003908.2 |
Summary | Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network. Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension. Plays a role in early autophagosome formation.[UniProtKB/Swiss-Prot Function] |
shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
Performance Guaranteed | OriGene guarantees that the sequences in the shRNA expression cassettes are verified to correspond to the target gene with 100% identity. One of the four constructs at minimum are guaranteed to produce 70% or more gene expression knock-down provided a minimum transfection efficiency of 80% is achieved. Western Blot data is recommended over qPCR to evaluate the silencing effect of the shRNA constructs 72 hrs post transfection. To properly assess knockdown, the gene expression level from the included scramble control vector must be used in comparison with the target-specific shRNA transfected samples. For non-conforming shRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the shRNA kit. To arrange for a free replacement with newly designed constructs, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled shRNA control (Western Blot data preferred). |
Citations (1)
The use of this RNAi has been cited in the following citations: |
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Dynamin and endocytosis are required for the fusion of osteoclasts and myoblasts
,Shin, NY;Choi, H;Neff, L;Wu, Y;Saito, H;Ferguson, SM;De Camilli, P;Baron, R;,
J. Cell Biol.
,PubMed ID 25287300
[CLTC]
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