Cleavage stimulation factor 2 (CSTF2) Human siRNA Oligo Duplex (Locus ID 1478)
CAT#: SR301049
CSTF2 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
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CNY 4,090.00
货期*
4周
规格
Cited in 2 publications. |
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经常一起买 (3)
Specifications
Product Data | |
Purity | HPLC purified |
Quality Control | Tested by ESI-MS |
Sequences | Available with shipment |
Stability | One year from date of shipment when stored at -20°C. |
# of transfections | Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM). |
Note | Single siRNA duplex (10nmol) can be ordered. |
Reference Data | |
RefSeq | NM_001306206, NM_001306209, NM_001325 |
Synonyms | CstF-64 |
Components | CSTF2 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 1478)Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmolIncluded - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml |
Summary | This gene encodes a nuclear protein with an RRM (RNA recognition motif) domain. The protein is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs. Specifically, this protein binds GU-rich elements within the 3'-untranslated region of mRNAs. [provided by RefSeq, Jul 2008] |
Performance Guranteed | OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency. For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required). |
Citations (2)
The use of this RNAi has been cited in the following citations: |
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Alternative polyadenylation factors link cell cycle to migration
,Mitra, M;Johnson, EL;Swamy, VS;Nersesian, LE;Corney, DC;Robinson, DG;Taylor, DG;Ambrus, AM;Jelinek, D;Wang, W;Batista, SL;Coller, HA;,
Genome Biol.
,PubMed ID 30360761
[CSTF2]
|
CstF-64 supports pluripotency and regulates cell cycle progression in embryonic stem cells through histone 3' end processing
,Youngblood, BA;Grozdanov, PN;MacDonald, CC;,
Nucleic Acids Res.
,PubMed ID 24957598
[CSTF2]
|
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