SAP97 (DLG1) Human siRNA Oligo Duplex (Locus ID 1739)
CAT#: SR301211
DLG1 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
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CNY 4,090.00
货期*
4周
规格
Cited in 1 publication. |
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经常一起买 (3)
Specifications
Product Data | |
Purity | HPLC purified |
Quality Control | Tested by ESI-MS |
Sequences | Available with shipment |
Stability | One year from date of shipment when stored at -20°C. |
# of transfections | Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM). |
Note | Single siRNA duplex (10nmol) can be ordered. |
Reference Data | |
RefSeq | NM_001098424, NM_001204386, NM_001204387, NM_001204388, NM_001290983, NM_004087, NM_001366213, NM_001366203, NM_001366205, NM_001366206, NM_001366208, NM_001366214, NM_001366216, NM_001366217, NM_001366218, NM_001366219, NR_158764, NM_001363865, NM_001366204, NM_001366207, NM_001366209, NM_001366210, NM_001366211, NM_001366212, NM_001366215, NM_001366220, NM_001366221, NM_001366222, NR_158765, NR_158766, NR_158767 |
Synonyms | DLGH1; hdlg; SAP-97; SAP97 |
Components | DLG1 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 1739)Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmolIncluded - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml |
Summary | This gene encodes a multi-domain scaffolding protein that is required for normal development. This protein may have a role in septate junction formation, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. A multitude of transcript variants deriving from alternative splicing and the use of multiple alternate promoter have been observed, including some splice variants that may be specific to brain and other tissues. An upstream uORF may regulate translation at some splice variants of this gene. [provided by RefSeq, Sep 2018] |
Performance Guranteed | OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency. For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required). |
Citations (1)
The use of this RNAi has been cited in the following citations: |
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SAP97 blocks the RXR ER retention signal of NMDA receptor subunit GluN1-3 through its SH3 domain
,Hong, X;Avetisyan, M;Ronilo, M;Standley, S;,
Biochim. Biophys. Acta
,PubMed ID 25499266
[DLG1]
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