SLUG (SNAI2) Human siRNA Oligo Duplex (Locus ID 6591)
CAT#: SR304468
SNAI2 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
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CNY 4,090.00
货期*
4周
规格
Cited in 1 publication. |
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经常一起买 (3)
SNAI2 (SLUG) mouse monoclonal antibody, clone OTI1A6 (formerly 1A6)
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Purity | HPLC purified |
Quality Control | Tested by ESI-MS |
Sequences | Available with shipment |
Stability | One year from date of shipment when stored at -20°C. |
# of transfections | Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM). |
Note | Single siRNA duplex (10nmol) can be ordered. |
Reference Data | |
RefSeq | NM_003068 |
Synonyms | SLUG; SLUGH; SLUGH1; SNAIL2; WS2D |
Components | SNAI2 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 6591)Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmolIncluded - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml |
Summary | This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008] |
Performance Guranteed | OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency. For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required). |
Citations (1)
The use of this RNAi has been cited in the following citations: |
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A novel microRNA regulator of prostate cancer epithelial-mesenchymal transition
,Bucay, N;Bhagirath, D;Sekhon, K;Yang, T;Fukuhara, S;Majid, S;Shahryari, V;Tabatabai, Z;Greene, KL;Hashimoto, Y;Shiina, M;Yamamura, S;Tanaka, Y;Deng, G;Dahiya, R;Saini, S;,
Cell Death Differ.
,PubMed ID 28498363
[SNAI2]
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