FISH (SH3PXD2A) Human siRNA Oligo Duplex (Locus ID 9644)
CAT#: SR306419
SH3PXD2A (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
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CNY 4,090.00
货期*
4周
规格
Cited in 1 publication. |
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经常一起买 (3)
SH3PXD2A mouse monoclonal antibody,clone OTI1F5
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Specifications
Product Data | |
Purity | HPLC purified |
Quality Control | Tested by ESI-MS |
Sequences | Available with shipment |
Stability | One year from date of shipment when stored at -20°C. |
# of transfections | Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM). |
Note | Single siRNA duplex (10nmol) can be ordered. |
Reference Data | |
RefSeq | NM_014631, NM_001365079 |
Synonyms | FISH; SH3MD1; TKS5 |
Components | SH3PXD2A (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 9644)Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmolIncluded - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml |
Summary | Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.[UniProtKB/Swiss-Prot Function] |
Performance Guranteed | OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency. For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required). |
Citations (1)
The use of this RNAi has been cited in the following citations: |
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The genomic landscape of schwannoma
,Agnihotri, S;Jalali, S;Wilson, MR;Danesh, A;Li, M;Klironomos, G;Krieger, JR;Mansouri, A;Khan, O;Mamatjan, Y;Landon-Brace, N;Tung, T;Dowar, M;Li, T;Bruce, JP;Burrell, KE;Tonge, PD;Alamsahebpour, A;Krischek, B;Agarwalla, PK;Bi, WL;Dunn, IF;Beroukhim, R;Fehlings, MG;Bril, V;Pagnotta, SM;Iavarone, A;Pugh, TJ;Aldape, KD;Zadeh, G;,
Nat. Genet.
,PubMed ID 27723760
[SH3PXD2A]
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