MCPIP1 (ZC3H12A) Human siRNA Oligo Duplex (Locus ID 80149)
CAT#: SR312813
ZC3H12A (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
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CNY 4,090.00
货期*
4周
规格
Cited in 3 publications. |
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经常一起买 (3)
Specifications
Product Data | |
Purity | HPLC purified |
Quality Control | Tested by ESI-MS |
Sequences | Available with shipment |
Stability | One year from date of shipment when stored at -20°C. |
# of transfections | Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM). |
Note | Single siRNA duplex (10nmol) can be ordered. |
Reference Data | |
RefSeq | NM_025079, NM_001323550, NM_001323551 |
Synonyms | dJ423B22.1; MCPIP; MCPIP-1; MCPIP1; Reg1 |
Components | ZC3H12A (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 80149)Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmolIncluded - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml |
Summary | ZC3H12A is an MCP1 (CCL2; MIM 158105)-induced protein that acts as a transcriptional activator and causes cell death of cardiomyocytes, possibly via induction of genes associated with apoptosis.[supplied by OMIM, Mar 2008] |
Performance Guranteed | OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency. For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required). |
Citations (3)
The use of this RNAi has been cited in the following citations: |
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An effective and efficient method of transfecting primary human chondrocytes in suspension
,Makki, MS;Akhtar, N;Haqqi, TM;,
Anal. Biochem
,PubMed ID 28315317
[ZC3H12A]
|
MicroRNA-9 promotes IL-6 expression by inhibiting MCPIP1 expression in IL-1ß-stimulated human chondrocytes
,Makki, MS;Haseeb, A;Haqqi, TM;,
Arthritis & rheumatology
,PubMed ID 25917063
[ZC3H12A]
|
MCPIP1 restricts HIV infection and is rapidly degraded in activated CD4+ T cells
,Liu, S;Qiu, C;Miao, R;Zhou, J;Lee, A;Liu, B;Lester, SN;Fu, W;Zhu, L;Zhang, L;Xu, J;Fan, D;Li, K;Fu, M;Wang, T;,
Proc. Natl. Acad. Sci. U.S.A. 19083-8
,PubMed ID 24191027
[ZC3H12A]
|
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