Cirhin (UTP4) Human siRNA Oligo Duplex (Locus ID 84916)
CAT#: SR313737
UTP4 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
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CNY 4,090.00
货期*
4周
规格
Cited in 1 publication. |
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经常一起买 (3)
Specifications
Product Data | |
Purity | HPLC purified |
Quality Control | Tested by ESI-MS |
Sequences | Available with shipment |
Stability | One year from date of shipment when stored at -20°C. |
# of transfections | Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM). |
Note | Single siRNA duplex (10nmol) can be ordered. |
Reference Data | |
RefSeq | NM_001318391, NM_032830 |
Synonyms | CIRH1A; CIRHIN; NAIC; TEX292 |
Components | UTP4 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 84916)Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmolIncluded - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml |
Summary | This gene encodes a WD40-repeat-containing protein that is localized to the nucleolus. Mutation of this gene causes North American Indian childhood cirrhosis, a severe intrahepatic cholestasis that results in transient neonatal jaundice, and progresses to periportal fibrosis and cirrhosis in childhood and adolescence. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] |
Performance Guranteed | OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency. For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required). |
Citations (1)
The use of this RNAi has been cited in the following citations: |
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Cockayne syndrome group A and B proteins converge on transcription-linked resolution of non-B DNA
,Scheibye-Knudsen, M;Tseng, A;Borch Jensen, M;Scheibye-Alsing, K;Fang, EF;Iyama, T;Bharti, SK;Marosi, K;Froetscher, L;Kassahun, H;Eckley, DM;Maul, RW;Bastian, P;De, S;Ghosh, S;Nilsen, H;Goldberg, IG;Mattson, MP;Wilson, DM;Brosh, RM;Gorospe, M;Bohr, VA;,
Proc. Natl. Acad. Sci. U.S.A.
,PubMed ID 27791127
[UTP4]
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