MYD88 Human siRNA Oligo Duplex (Locus ID 4615)
CAT#: SR321049
MYD88 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
Need single siRNA in bulk?
Get a free quote
SR321049 is the updated version of SR303028.
CNY 4,090.00
货期*
4周
规格
Cited in 2 publications. |
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
经常一起买 (3)
MYD88 mouse monoclonal antibody, clone OTI2B2 (formerly 2B2)
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Purity | HPLC purified |
Quality Control | Tested by ESI-MS |
Sequences | Available with shipment |
Stability | One year from date of shipment when stored at -20°C. |
# of transfections | Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM). |
Note | Single siRNA duplex (10nmol) can be ordered. |
Reference Data | |
RefSeq | NM_001172566, NM_001172567, NM_001172568, NM_001172569, NM_002468, NM_001365877, NM_001365876 |
Synonyms | IMD68; MYD88D |
Components | MYD88 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 4615)Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmolIncluded - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml |
Summary | This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010] |
Performance Guranteed | OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency. For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required). |
Citations (2)
The use of this RNAi has been cited in the following citations: |
---|
MicroRNA-214 promotes the calcification of human aortic valve interstitial cells through the acceleration of inflammatory reactions with activated MyD88/NF-κB signaling
,Zheng, D;Zang, Y;Xu, H;Wang, Y;Cao, X;Wang, T;Pan, M;Shi, J;Li, X;,
Clin Res Cardiol
,PubMed ID 30519780
[MYD88]
|
Cytomegalovirus Promotes Intestinal Macrophage-mediated Mucosal Inflammation through Induction of Smad7
,null,
Mucosal immunology
,PubMed ID 30076393
[MYD88]
|
Documents
Product Manuals |
FAQs |
SDS |
Customer
Reviews
Loading...