Nat1 Mouse siRNA Oligo Duplex (Locus ID 17960)
CAT#: SR408355
Nat1 (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each
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CNY 4,090.00
货期*
7周
规格
Cited in 2 publications. |
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经常一起买 (2)
Specifications
Product Data | |
Purity | HPLC purified |
Quality Control | Tested by ESI-MS |
Sequences | Available with shipment |
Stability | One year from date of shipment when stored at -20°C. |
# of transfections | Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM). |
Note | Single siRNA duplex (10nmol) can be ordered. |
Reference Data | |
RefSeq | NM_008673 |
Synonyms | Nat-1 |
Components | Nat1 (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 17960)Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmolIncluded - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml |
Summary | Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Isoniazid, 2-aminofluorene and anisidine are preferred substrates for NAT-1. No activity with p-aminobenzoic acid (PABA) nor SMZ.[UniProtKB/Swiss-Prot Function] |
Performance Guranteed | OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency. For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required). |
Citations (2)
The use of this RNAi has been cited in the following citations: |
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Nat1 Deficiency Is Associated with Mitochondrial Dysfunction and Exercise Intolerance in Mice
,Chennamsetty, I;Coronado, M;Contrepois, K;Keller, MP;Carcamo-Orive, I;Sandin, J;Fajardo, G;Whittle, AJ;Fathzadeh, M;Snyder, M;Reaven, G;Attie, AD;Bernstein, D;Quertermous, T;Knowles, JW;,
Cell Rep
,PubMed ID 27705799
[Nat1]
|
Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene
,null,
The Journal of Clinical Investigation
,PubMed ID 25798622
[Nat1]
|
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