Sparc Mouse siRNA Oligo Duplex (Locus ID 20692)
CAT#: SR408816
Sparc (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each
Need single siRNA in bulk?
Get a free quote
CNY 4,090.00
货期*
4周
规格
Cited in 2 publications. |
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
经常一起买 (2)
Specifications
Product Data | |
Purity | HPLC purified |
Quality Control | Tested by ESI-MS |
Sequences | Available with shipment |
Stability | One year from date of shipment when stored at -20°C. |
# of transfections | Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM). |
Note | Single siRNA duplex (10nmol) can be ordered. |
Reference Data | |
RefSeq | NM_001290817, NM_009242 |
Synonyms | BM-40; ON |
Components | Sparc (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 20692)Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmolIncluded - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml |
Summary | Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.[UniProtKB/Swiss-Prot Function] |
Performance Guranteed | OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency. For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required). |
Citations (2)
The use of this RNAi has been cited in the following citations: |
---|
Surface modification of polymer nanoparticles with native albumin for enhancing drug delivery to solid tumors
,Hyun, H;Park, J;Willis, K;Park, JE;Lyle, LT;Lee, W;Yeo, Y;,
Biomaterials
,PubMed ID 30048910
[SPARC]
|
Glioblastoma-secreted soluble CD44 activates tau pathology in the brain
,Lim, S;Kim, D;Ju, S;Shin, S;Cho, IJ;Park, SH;Grailhe, R;Lee, C;Kim, YK;,
Exp. Mol. Med.
,PubMed ID 29622771
[SPARC]
|
Documents
Product Manuals |
FAQs |
SDS |
Customer
Reviews
Loading...