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PARP1 Rabbit Polyclonal Antibody
CAT＃: TA321379S
Anti-PARP1 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommend Dilution | WB: 500-2000 WB positive control: Jurkat and Hela cells IHC: 25-100 Positive control: Human liver cancer Predicted cell location: Nucleus |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 12-21 amino acids of human poly (ADP-ribose) polymerase 1 |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 113 kDa |
| Gene Name | poly(ADP-ribose) polymerase 1 |
| Database Link | |
| Background | This gene encodes a chromatin-associated enzyme; poly(ADP-ribosyl)transferase; which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation; proliferation; and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition; this enzyme may be the site of mutation in Fanconi anemia; and may participate in the pathophysiology of type I diabetes. |
| Synonyms | ADPRT; ADPRT 1; ADPRT1; ARTD1; pADPRT-1; PARP; PARP-1; PPOL |
| Reference Data | |
| Protein Families | Druggable Genome, Stem cell - Pluripotency, Transcription Factors |
| Protein Pathways | Base excision repair |
Documents
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Rabbit anti-PARP1 Polyclonal Antibody
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