ALKBH1 Rabbit Polyclonal Antibody

CAT#: TA321739

Anti-ALKBH1 Rabbit Polyclonal Antibody

Size: 25 ul 100 ul



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CNY 1,999.00

CNY 3,280.00


货期*
2周

规格
    • 100 ul

Product images

经常一起买 (4)
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Recombinant protein of human alkB, alkylation repair homolog 1 (E. coli) (ALKBH1), 20 µg
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Recombinant protein of human alkB, alkylation repair homolog 1 (E. coli) (ALKBH1), 100 µg
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Specifications

Product Data
Applications WB
Recommend Dilution WB: 500-2000
WB positive control: Mouse pancreas tissue
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen Fusion protein corresponding to N terminal 250 amino acids of human alkB, alkylation repair homolog 1 (E. coli)
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 44 kDa
Gene Name alkB homolog 1, histone H2A dioxygenase
Background This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. Requires molecular oxygen; alpha-ketoglutarate and iron. May have a role in placental trophoblast lineage differentiation. Has DNA lyase activity and introduces double-stranded breaks at abasic sites. Cleaves both single-stranded DNA and double-stranded DNA at abasic sites; with the greatest activity towards double-stranded DNA with two abasic sites.
Synonyms ABH; ABH1; alkB; ALKBH; hABH
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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