ARSB Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	ARSB antibody was raised against a 16 amino acid peptide near the carboxy terminus of human ARSB
Formulation	ARSB Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	ARSB Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 59 kDa; Observed: 57 kDa
Gene Name	arylsulfatase B
Database Link	NP_000037 Entrez Gene 11881 MouseEntrez Gene 25227 RatEntrez Gene 411 Human UniProt ID P15848
Background	Aryl sulfatase B (ARSB) forms a homodimer that hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate (1). ARSB localizes to the lysozyme as well as to the extracellular matrix (2). Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B (3), and can be treated with exogenous ARSB (4).
Synonyms	ASB; G4S; MPS6
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Glycosaminoglycan degradation, Lysosome, Metabolic pathways

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