DNMT3B Rabbit Polyclonal Antibody

CAT#: TA327439

DNMT3B Rabbit Polyclonal Antibody



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热销推荐

CNY 1,999.00

CNY 2,700.00


货期*
2周

规格
    • 100 ul

Product images

经常一起买 (4)
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Recombinant protein of human DNA (cytosine-5-)-methyltransferase 3 beta (DNMT3B), transcript variant 1, 20 µg
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Recombinant protein of human DNA (cytosine-5-)-methyltransferase 3 beta (DNMT3B), transcript variant 1, 100 µg
    • 100 ug

CNY 9,998.00

Specifications

Product Data
Applications ICC/IF, WB
Recommend Dilution WB 1:200 - 1:1000
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen A synthetic peptide of human DNMT3B
Formulation PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 96 kDa
Gene Name DNA (cytosine-5-)-methyltransferase 3 beta
Background CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. [provided by RefSeq, May 2011]
Synonyms ICF; ICF1; M.HsaIIIB
Reference Data
Protein Families Druggable Genome, Embryonic stem cells, Induced pluripotent stem cells, Stem cell - Pluripotency
Protein Pathways Cysteine and methionine metabolism, Metabolic pathways
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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