PPP2R4 (PTPA) Rabbit Polyclonal Antibody
CAT#: TA332460
Rabbit anti-PPP2R4 Polyclonal Antibody
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Specifications
Product Data | |
Applications | IF |
Recommend Dilution | WB 1:500 - 1:2000, IHC 1:50- 1:200, IF 1:50- 1:200 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human PPP2R4 |
Formulation | Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | protein phosphatase 2 phosphatase activator |
Database Link | |
Background | Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Synonyms | PP2A; PR53; PTPA |
Reference Data | |
Protein Families | Druggable Genome, Phosphatase |
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