PD1 (PDCD1) Mouse Monoclonal Antibody [Clone ID: UMAB199]
CAT#: UM800091
PD-1 (PDCD1) mouse monoclonal antibody,clone UMAB199
Size: 30 ul
Formulation: Carrier-Free
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CNY 2,999.00
Cited in 6 publications. |
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Clone Name | UMAB199 |
Applications | 10k-ChIP, IF, IHC, WB |
Recommend Dilution | IHC 1:1000, WB 1:500, IF 1:100 |
Reactivity | Human, Mouse, Dog, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human PDCD1 (NP_005009) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.5~1.0 mg/ml (Lot Dependent) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 29.2 kDa |
Gene Name | programmed cell death 1 |
Database Link | |
Background | This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul |
Synonyms | CD279; hPD-1; hPD-l; hSLE1; PD-1; PD1; SLEB2 |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Cell adhesion molecules (CAMs), T cell receptor signaling pathway |
Citations (6)
The use of this Antibodies has been cited in the following citations: |
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Reprogramming of PD-1 + M2-like tumor-associated macrophages with anti–PD-L1 and lenalidomide in cutaneous T cell lymphoma
,null,
JCI Insight
,PubMed ID 37427589
[PDCD1]
|
Tumor immune contexture is a determinant of anti-CD19 CAR T cell efficacy in large B cell lymphoma
,null,
Nature Medicine
,PubMed ID 36038629
[PDCD1]
|
Identification of a Distinct miRNA Regulatory Network in the Tumor Microenvironment of Transformed Mycosis Fungoides
,null,
Cancers
,PubMed ID 34831008
[PDCD1]
|
Multi-panel immunofluorescence analysis of tumor infiltrating lymphocytes in triple negative breast cancer: Evolution of tumor immune profiles and patient prognosis
,He, TF;Yost, SE;Frankel, PH;Dagis, A;Cao, Y;Wang, R;Rosario, A;Tu, TY;Solomon, S;Schmolze, D;Mortimer, J;Lee, P;Yuan, Y;,
PLoS ONE
,PubMed ID 32150594
[PDCD1]
|
Mycoplasma bovis-Induced Inhibition of Bovine Peripheral Blood Mononuclear Cell Proliferation Is Ameliorated after Blocking the Immune-Inhibitory Programmed Death 1 Receptor
,Suleman, M;Cyprian, FS;Jimbo, S;Maina, T;Prysliak, T;Windeyer, C;Perez-Casal, J;,
Infect. Immun.
,PubMed ID 29311234
[PDCD1]
|
Immune Activation and Benefit From Avelumab in EBV-Positive Gastric Cancer
,Panda, A;Mehnert, JM;Hirshfield, KM;Riedlinger, G;Damare, S;Saunders, T;Kane, M;Sokol, L;Stein, MN;Poplin, E;Rodriguez-Rodriguez, L;Silk, AW;Aisner, J;Chan, N;Malhotra, J;Frankel, M;Kaufman, HL;Ali, S;Ross, JS;White, EP;Bhanot, G;Ganesan, S;,
J. Natl. Cancer Inst.2017
,PubMed ID 29155997
[PDCD1]
|
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
UM800091CF | Carrier-free (BSA/glycerol-free) PD-1 (PDCD1) mouse monoclonal antibody,clone UMAB199 |
CNY 4,999.00 |
|
UM870091 | PD-1 (PDCD1) mouse monoclonal antibody,clone UMAB199 |
CNY 1,150.00 |