bcl 6 (BCL6) Rabbit Monoclonal Antibody [Clone ID: UMAB299]
CAT#: UM970004
BCL6 Rabbit monoclonal antibody,clone UMAB299
Size: 100 ul
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CNY 1,430.00
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Specifications
Product Data | |
Clone Name | UMAB299 |
Applications | IHC |
Recommend Dilution | IHC 1:1200 |
Reactivity | Human |
Host | Rabbit |
Clonality | Monoclonal |
Immunogen | Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human BCL6 (NP_001697). The exact sequence is proprietary. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1.00mg/ml |
Purification | Purified from cell culture supernatant by affinity chromatography(protein A/G) |
Conjugation | Unconjugated |
Predicted Protein Size | 78.7 kDa |
Gene Name | BCL6 transcription repressor |
Database Link | |
Background | The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015] |
Synonyms | BCL5; BCL6A; LAZ3; ZBTB27; ZNF51 |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
UM900004 | BCL6 Rabbit monoclonal antibody,clone UMAB299 |
CNY 3,600.00 |