United States
Germany
Japan
United Kingdom
China
Eng (NM_007932) Mouse Untagged Clone
CAT＃: MC202877
Eng (untagged) - Mouse endoglin (Eng), transcript variant 1, (10ug)
CNY 4,872.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AI528660; AI662476; CD105; Endo; S-endoglin |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC029080 sequence for NM_007932
CGGACGCGTGGGCCGCCGACAGCTGCTGCCCGAAAGAGCCCAGTGACTCTTTCCCACCACCCAGTCAGCT AGAGACTCCTGCCCTGCTGTGAGTCTCGAGCCCACTTCTCCTGACTTCTCCGCCGCCACCTCAGAAGGCT GGAGCAGGGACGTGGTCGCTCCGGCCGCCTGCTCCCTTCGGATCCCCGCGCGAACCCACGCAGGCCCCGG CGCCCGCCCGCAGCCTTACCTCTGGATACCGGATAAGGCCCAGCGCACAGACTCCCGGGTGGACAGCATG GACCGTGGCGTGCTCCCTCTGCCCATTACCCTGCTGTTTGTCATCTATAGCTTTGTACCCACAACAGGTC TCGCAGAAAGAGTCGGCTGTGATCTACAGCCTGTGGACCCCACAAGGGGTGAGGTGACGTTTACCACCAG CCAGGTCTCCGAGGGCTGTGTAGCTCAGGCTGCCAATGCTGTGCGTGAAGTCCACGTTCTCTTCCTGGAT TTTCCCGGAATGCTGTCACATCTGGAGCTGACTCTTCAGGCATCCAAGCAAAATGGCACGGAGACCCAGG AGGTGTTCCTGGTCCTCGTTTCGAACAAAAATGTCTTCGTGAAGTTCCAGGCCCCGGAAATCCCATTGCA CTTGGCCTACGACTCCAGCCTGGTCATCTTCCAAGGACAGCCAAGAGTCAACATCACAGTGCTACCATCC CTTACCTCCAGGAAACAGATCCTCGACTGGGCAGCCACCAAGGGCGCCATCACCTCGATAGCAGCACTGG ATGACCCCCAAAGCATCGTCCTCCAGTTGGGCCAAGACCCAAAGGCACCATTCTTGTGCTTGCCAGAAGC TCACAAGGACATGGGCGCCACACTTGAATGGCAACCACGAGCCCAGACCCCAGTCCAAAGCTGTCGCTTG GAAGGTGTGTCTGGCCACAAGGAGGCCTACATCCTGAGGATCCTGCCAGGTTCTGAGGCCGGGCCCCGGA CGGTGACCGTAATGATGGAACTGAGTTGCACATCTGGGGACGCCATTCTCATCCTGCATGGTCCTCCATA TGTCTCCTGGTTCATCGACATCAACCACAGCATGCAGATCTTGACCACAGGTGAATACTCCGTCAAGATC TTTCCAGGAAGCAAGGTCAAAGGCGTGGAGCTCCCAGACACACCCCAAGGCCTGATAGCGGAGGCCCGCA AGCTCAATGCCAGCATTGTCACCTCCTTTGTAGAGCTCCCTCTGGTCAGCAATGTCTCCCTGAGGGCCTC CAGCTGCGGTGGTGTGTTCCAGACCACCCCTGCACCCGTTGTGACCACACCTCCCAAGGACACATGCAGC CCCGTGCTACTCATGTCCCTGATCCAGCCAAAGTGTGGCAATCAGGTCATGACTCTGGCACTCAATAAAA AACACGTGCAGACTCTCCAGTGCACCATCACAGGCCTGACTTTCTGGGACTCCAGCTGCCAGGCTGAAGA CACTGACGACCATCTTGTCCTGAGTAGCGCCTACTCCAGCTGCGGCATGAAAGTGACAGCCCATGTGGTC AGCAATGAGGTGATCATCAGTTTCCCGTCAGGCTCACCACCACTTCGGAAAAAGGTACAGTGCATCGACA TGGACAGCCTCTCCTTCCAGCTGGGCCTCTACCTCAGCCCGCACTTCCTCCAGGCATCCAACACCATCGA ACTAGGCCAGCAGGCCTTCGTACAGGTGAGCGTGTCTCCATTGACCTCTGAGGTCACAGTCCAGCTAGAT AGCTGCCATCTGGACTTGGGGCCCGAAGGGGACATGGTGGAACTCATCCAGAGCCGAACAGCCAAGGGCA GCTGTGTGACCTTGCTGTCTCCAAGCCCTGAAGGTGACCCACGCTTCAGCTTCCTCCTCCGGGTCTACAT GGTGCCCACACCCACCGCTGGCACCCTCAGTTGCAACTTAGCTCTGCGCCCTAGCACCTTGTCCCAGGAA GTCTACAAGACAGTCTCCATGCGCCTGAACATCGTCAGCCCTGACCTGTCTGGTAAAGGCCTTGTCCTGC CCTCTGTACTGGGTATCACCTTTGGTGCCTTCCTGATTGGGGCCCTGCTCACAGCTGCACTCTGGTACAT CTATTCTCACACACGTGGCCCCAGCAAGCGGGAGCCCGTGGTGGCAGTGGCTGCCCCGGCCTCCTCTGAG AGCAGCAGTACCAACCACAGCATCGGGAGCACCCAGAGCACCCCCTGCTCCACCAGCAGCATGGCGTAGT GCCCAGCCTGGAGCCTCGGGGAGCCCCCCAGCCAGCCCTTGCCCTGCAGGAGAGACCGAGCAGCCACAAG CTGGAAACCACCGGCCATGAACTTGTCCCAGGAACCAAACACCTCCCCTGCACCTGTTCATTCCTCCCAG TGGAGACTTCAGATTGGAATACCTTGGGATCTCCTCACCCCACTTTACAGAACTGCCCAATCCAGGGGCT CTGGGATATGGCTGCCCGGGATTACAGAAAGACACGGCACTGCCGTGCACACCCATGCTGCTTAGAAGCC TAAGCCTCTGCCTTCAAGCTGGATCCTGTGCAGGGTGGGCAGGCAAGAACTCAGACATGCCCAGCCTAGC CCAGGGCGGCCTGCATCTGGCCCCAGAAGCCTCCTCACCTGGACTGGCACAACTTCGGTTGGGGAAACAG AAGCTGAGGGAGCTTAGATGGGGTGGGGGATCCAAGCCCCTCCCAGCCCACCCATTGGCCAGGCAGCAGG GGGGAGTGGCCAGGCGGCTGGTTGTGGGCCAAGTCCTGCATATTCACTAATAAATCAGACATGAAACCAG AAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_007932 |
| Insert Size | 1962 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC029080, AAH29080 |
| RefSeq Size | 2824 bp |
| RefSeq ORF | 1962 bp |
| Locus ID | 13805 |
| UniProt ID | Q63961 |
| Gene Summary | Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis (PubMed:10625534). Required for normal structure and integrity of adult vasculature (By similarity). Regulates the migration of vascular endothelial cells (PubMed:17540773). Required for normal extraembryonic angiogenesis and for embryonic heart development (PubMed:10625534). May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis (PubMed:28530658). May play a role in the binding of endothelial cells to integrins. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade that ultimately leads to the activation of SMAD transcription factors (PubMed:23300529). Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGFB1 signaling through SMAD3 (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). This is also known as L-endoglin. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG209782 | Eng (tGFP-tagged) - Mouse endoglin (Eng) |
CNY 5,230.00 |
|
| MG222686 | Eng (tGFP-tagged) - Mouse endoglin (Eng) transcript variant 1, (10ug) |
CNY 6,270.00 |
|
| MR222686 | Eng (Myc-DDK-tagged) - Mouse endoglin (Eng), transcript variant 1 |
CNY 4,872.00 |
|
| MR222686L3 | Lenti ORF clone of Eng (Myc-DDK-tagged) - Mouse endoglin (Eng), transcript variant 1 |
CNY 7,600.00 |
|
| MR222686L4 | Lenti ORF clone of Eng (mGFP-tagged) - Mouse endoglin (Eng), transcript variant 1 |
CNY 7,600.00 |
