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Sec61a1 (NM_016906) Mouse Untagged Clone
CAT＃: MC216417
Sec61a1 (untagged) - Mouse Sec61 alpha 1 subunit (S. cerevisiae) (Sec61a1), (10ug)
CNY 6,180.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AA408394; AA410007; Sec61a |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC216417 representing NM_016906
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGATCAAATTTCTGGAAGTCATCAAGCCATTCTGTGTCATCTTGCCGGAAATTCAGAAGCCAGAGA GAAAGATTCAGTTTAAGGAGAAAGTTCTGTGGACAGCCATCACCCTCTTCATCTTCTTAGTATGCTGTCA GATCCCCCTGTTTGGCATCATGTCTTCAGACTCAGCTGACCCGTTCTACTGGATGCGAGTGATTCTGGCC TCTAACAGAGGTACCTTAATGGAGCTGGGCATCTCTCCTATTGTCACCTCCGGTCTTATCATGCAGCTCT TAGCTGGTGCCAAGATAATTGAAGTTGGGGACACCCCGAAAGACCGAGCTCTCTTCAATGGAGCCCAGAA GTTGTTTGGAATGATCATTACTATCGGTCAGTCCATTGTGTATGTGATGACGGGCATGTACGGGGACCCT TCGGAGATGGGTGCTGGAATCTGCCTGCTGATCACCATTCAGCTCTTTGTTGCTGGCTTAATTGTCCTAC TTTTGGATGAACTTCTGCAAAAAGGGTACGGCTTGGGCTCTGGCATTTCTCTCTTCATTGCGACTAACAT CTGTGAGACCATTGTGTGGAAGGCATTCAGCCCCACCACTGTCAACACTGGCCGAGGGATGGAATTCGAA GGCGCCATCATAGCGCTATTCCACCTGCTGGCCACCCGCACAGACAAGGTCCGAGCCCTTCGAGAGGCAT TCTACCGCCAGAACCTCCCCAACCTCATGAACCTGATTGCCACCATCTTCGTCTTTGCCGTTGTCATCTA TTTCCAGGGCTTCCGAGTGGACCTTCCAATCAAGTCGGCGCGTTACCGAGGCCAGTACAACACCTATCCC ATCAAGCTCTTCTACACCTCCAACATCCCCATCATCTTGCAGTCTGCTCTGGTGTCCAACCTGTATGTCA TCTCCCAGATGCTGTCAGCACGCTTCAGTGGCAACCTGCTGGTTAGCCTGCTGGGCACCTGGTCGGATAC ATCATCTGGGGGCCCAGCCCGAGCTTACCCCGTTGGTGGCCTGTGTTACTACCTGTCTCCTCCGGAATCG TTCGGCTCAGTGCTGGAGGACCCTGTCCATGCGGTCGTGTACATCGTGTTCATGCTGGGCTCCTGTGCAT TCTTCTCCAAAACATGGATCGAAGTCTCAGGTTCTTCTGCCAAAGATGTTGCAAAGCAGCTGAAGGAGCA GCAGATGGTGATGAGGGGCCACAGGGAGACCTCCATGGTGCATGAGCTCAACCGGTACATCCCCACAGCC GCAGCCTTTGGTGGGCTGTGCATTGGGGCCCTCTCTGTCCTGGCTGACTTCCTGGGTGCTATCGGGTCTG GAACTGGGATCCTGCTTGCGGTCACCATCATCTACCAGTACTTTGAGATCTTCGTCAAGGAACAGAGCGA GGTGGGCAGCATGGGAGCCCTTCTCTTCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_016906 |
| Insert Size | 1431 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_016906.4, NP_058602.1 |
| RefSeq Size | 3039 bp |
| RefSeq ORF | 1431 bp |
| Locus ID | 53421 |
| UniProt ID | P61620 |
| Gene Summary | Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across endoplasmic reticulum (ER). Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides. May cooperate with auxiliary protein SEC62, SEC63 and HSPA5/BiP to enable post-translational transport of small presecretory proteins. Controls the passive efflux of calcium ions from the ER lumen to the cytosol through SEC61 channel, contributing to the maintenance of cellular calcium homeostasis (By similarity). Plays a critical role in nephrogenesis, specifically at pronephros stage (PubMed:27392076).[UniProtKB/Swiss-Prot Function] |
Documents
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| FAQs |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG207628 | Sec61a1 (tGFP-tagged) - Mouse Sec61 alpha 1 subunit (S. cerevisiae) (Sec61a1) |
CNY 3,710.00 |
|
| MR207628 | Sec61a1 (Myc-DDK-tagged) - Mouse Sec61 alpha 1 subunit (S. cerevisiae) (Sec61a1) |
CNY 3,656.00 |
|
| MR207628L3 | Lenti ORF clone of Sec61a1 (Myc-DDK-tagged) - Mouse Sec61 alpha 1 subunit (S. cerevisiae) (Sec61a1) |
CNY 5,230.00 |
|
| MR207628L4 | Lenti ORF clone of Sec61a1 (mGFP-tagged) - Mouse Sec61 alpha 1 subunit (S. cerevisiae) (Sec61a1) |
CNY 5,230.00 |
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