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Sec61a1 (NM_016906) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR207628L3V
- LentiORF®
-
Lenti ORF particles, Sec61a1 (Myc-DDK-tagged) - Mouse Sec61 alpha 1 subunit (S. cerevisiae) (Sec61a1), 200ul, >10^7 TU/mL
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CNY 9,215.00
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Specifications
| Product Data | |
| Product Name | Sec61a1 (NM_016906) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | AA408394; AA410007; Sec61a |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_016906 |
| ORF Size | 1431 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR207628).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_016906.2, NP_058602.1 |
| RefSeq Size | 3039 bp |
| RefSeq ORF | 1431 bp |
| Locus ID | 53421 |
| Gene Summary | Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across endoplasmic reticulum (ER). Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides. May cooperate with auxiliary protein SEC62, SEC63 and HSPA5/BiP to enable post-translational transport of small presecretory proteins. Controls the passive efflux of calcium ions from the ER lumen to the cytosol through SEC61 channel, contributing to the maintenance of cellular calcium homeostasis (By similarity). Plays a critical role in nephrogenesis, specifically at pronephros stage (PubMed:27392076).[UniProtKB/Swiss-Prot Function] |
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