United States
Germany
Japan
United Kingdom
China
Epha7 (NM_010141) Mouse Untagged Clone
CAT＃: MC223037
Epha7 (untagged) - Mouse Eph receptor A7 (Epha7), transcript variant 1, (10ug)
CNY 12,920.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | Cek11; Ebk; Ehk3; Hek11; Mdk1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC223037 representing NM_010141
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGTTGTTCAAACTCGGTTCCCTTCGTGGATTATTTTGTGTTACATCTGGCTGCTTGGCTTTGCACACA CGGGGGAGGCGCAGGCTGCGAAGGAAGTACTATTACTGGACTCGAAAGCACAACAAACAGAATTGGAATG GATTTCCTCTCCACCCAGTGGGTGGGAAGAAATTAGTGGTTTGGATGAGAACTACACTCCGATAAGAACA TACCAGGTGTGCCAGGTCATGGAGCCCAACCAGAACAACTGGCTGCGGACTAACTGGATTTCTAAAGGCA ACGCACAAAGGATTTTTGTAGAATTGAAATTCACCTTGAGGGATTGTAATAGTCTTCCCGGAGTCCTGGG AACTTGCAAGGAAACGTTTAATTTGTACTATTATGAAACAGACTACGACACCGGCAGGAATATACGAGAA AACCTTTATGTTAAAATAGACACCATTGCTGCAGATGAAAGTTTCACACAAGGTGACCTTGGTGAAAGAA AGATGAAGCTGAACACTGAGGTGAGAGAGATTGGACCTTTGTCCAAAAAGGGATTCTATCTTGCCTTTCA GGATGTAGGGGCTTGCATAGCATTGGTTTCTGTCAAAGTGTACTACAAGAAGTGCTGGTCCATTGTTGAG AACTTAGCTGTCTTTCCAGATACAGTGACTGGTTCGGAATTTTCCTCCTTAGTCGAGGTCCGTGGGACAT GTGTCAGCAGTGCCGAGGAAGAGGCAGAAAATTCCCCCAGAATGCATTGCAGTGCAGAAGGAGAGTGGCT AGTACCCATTGGAAAATGCATCTGCAAAGCAGGCTATCAGCAAAAAGGGGACACTTGCGAACCCTGTGGC CGCAGGTTCTACAAATCTTCCTCTCAGGATCTCCAGTGTTCTCGTTGTCCAACCCACAGCTTCTCTGACC GAGAAGGATCATCCAGGTGTGAATGTGAAGATGGGTACTACAGAGCTCCTTCTGATCCACCATACGTTGC ATGCACGAGGCCTCCCTCTGCACCACAGAACCTTATTTTCAATATCAATCAAACGACTGTAAGTTTGGAA TGGAGTCCTCCGGCTGACAACGGGGGAAGAAACGATGTCACCTACAGAATACTGTGTAAGCGGTGCAGTT GGGAACAGGGAGAATGTGTGCCATGCGGAAGTAACATTGGATACATGCCCCAGCAGACGGGATTAGAGGA TAACTATGTCACTGTCATGGACCTACTTGCCCATGCAAATTACACTTTCGAAGTTGAAGCTGTAAATGGA GTTTCGGACTTAAGCAGATCCCAGAGGCTCTTCGCTGCTGTTAGCATCACCACCGGTCAAGCAGCTCCCT CGCAAGTGAGTGGAGTCATGAAGGAGCGAGTACTGCAGCGGAGTGTGCAGCTTTCCTGGCAGGAGCCGGA GCATCCCAATGGAGTCATCACGGAATATGAAATCAAGTATTATGAGAAAGATCAACGGGAAAGGACGTAC TCAACACTCAAAACCAAGTCCACCTCCGCCTCCATTAATAATCTGAAACCGGGAACAGTGTACGTCTTTC AGATCCGGGCGGTCACTGCTGCCGGTTATGGAAACTACAGCCCTAGGCTTGATGTTGCCACACTTGAGGA AGCTTCAGGTAAAATGTTTGAAGCGACAGCAGTCTCCAGTGAACAGAATCCTGTCATCATAATTGCTGTA GTGGCTGTAGCAGGGACCATCATCTTGGTGTTCATGGTGTTCGGCTTCATCATTGGAAGAAGGCACTGTG GTTATAGCAAGGCTGACCAAGAAGGGGATGAAGAACTCTACTTTCATTTTAAATTTCCAGGCACCAAAAC CTACATTGACCCTGAAACCTATGAGGACCCAAATAGAGCTGTCCATCAATTCGCCAAGGAGCTAGATGCC TCCTGTATTAAAATTGAGCGTGTGATTGGTGCAGGAGAATTTGGAGAAGTTTGCAGTGGTCGTTTGAAAC TTCCGGGGAAGAGAGATGTTGCAGTGGCCATAAAAACCCTGAAAGTTGGTTACACAGAAAAGCAAAGGAG GGACTTTTTATGCGAAGCAAGCATCATGGGGCAATTTGACCACCCAAATGTCGTCCATTTGGAAGGGGTT GTTACAAGAGGGAAGCCTGTCATGATTGTGATAGAGTTCATGGAGAATGGAGCCCTGGATGCATTTCTCA GGAAACACGATGGGCAGTTTACAGTCATTCAGTTGGTAGGAATGTTGAGAGGTATTGCCGCTGGGATGCG ATACTTGGCTGATATGGGATACGTTCACAGGGACCTTGCAGCGCGCAACATCCTTGTCAACAGCAATCTT GTTTGTAAAGTGTCAGATTTTGGCCTTTCCCGGGTTATAGAGGATGATCCCGAAGCTGTCTACACCACGA CTGGTGGAAAAATTCCAGTAAGGTGGACTGCACCGGAAGCCATTCAATACCGGAAGTTCACCTCAGCCAG CGATGTGTGGAGCTATGGGATTGTCATGTGGGAAGTGATGTCTTATGGAGAAAGACCTTACTGGGACATG TCAAATCAAGATGTCATTAAAGCGATAGAAGAAGGTTATCGTTTGCCGGCGCCCATGGATTGCCCAGCTG GTCTTCACCAGCTAATGCTGGATTGTTGGCAGAAAGATCGGGCGGAAAGGCCAAAGTTTGAGCAGATAGT CGGAATTCTAGACAAAATGATTCGAAACCCAAGTAGTCTGAAAACACCCCTGGGAACTTGTAGTAGACCC TTAAGCCCTCTTCTGGACCAGAGCACTCCTGACTTCACTGCCTTCTGTTCAGTTGGAGAATGGTTGCAAG CTATTAAAATGGAAAGGTATAAGGACAACTTCACAGCAGCGGGTTACAACTCACTCGAGTCAGTGGCCAG GATGACTATCGATGATGTGATGAGTTTAGGGATCACACTGGTTGGCCATCAAAAGAAGATCATGAGCAGC ATCCAGACTATGCGGGCACAAATGTTGCATTTACACGGAACAGGCATCCAAGTGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_010141 |
| Insert Size | 2997 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_010141.4, NP_034271.3 |
| RefSeq Size | 6750 bp |
| RefSeq ORF | 2997 bp |
| Locus ID | 13841 |
| UniProt ID | Q61772 |
| Gene Summary | Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion. Has a repellent activity on axons and is for instance involved in the guidance of corticothalamic axons and in the proper topographic mapping of retinal axons to the colliculus. May also regulate brain development through a caspase(CASP3)-dependent proapoptotic activity. Forward signaling may result in activation of components of the ERK signaling pathway including MAP2K1, MAP2K2, MAPK1 AND MAPK3 which are phosphorylated upon activation of EPHA7. Isoform 4 which lacks the kinase domain may regulate isoform 1 adhesive properties.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG226270 | Epha7 (tGFP-tagged) - Mouse Eph receptor A7 (Epha7) transcript variant 1, (10ug) |
CNY 9,600.00 |
|
| MR226270 | Epha7 (Myc-DDK-tagged) - Mouse Eph receptor A7 (Epha7), transcript variant 1 |
CNY 7,312.00 |
|
| MR226270L3 | Lenti ORF clone of Epha7 (Myc-DDK-tagged) - Mouse Eph receptor A7 (Epha7), transcript variant 1 |
CNY 10,640.00 |
|
| MR226270L4 | Lenti ORF clone of Epha7 (mGFP-tagged) - Mouse Eph receptor A7 (Epha7), transcript variant 1 |
CNY 10,640.00 |
