Mink1 (NM_001045964) Mouse Untagged Clone
CAT#: MC224283
Mink1 (untagged) - Mouse misshapen-like kinase 1 (zebrafish) (Mink1), transcript variant 4, (10ug)
CNY 17,200.00
货期*
14周
规格
Product images
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经常一起买 (3)
Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Synonyms | B55; Map4k6; MINK; Ysk2 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MC224283 representing NM_001045964
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGCGACCCAGCCCCCGCCCGCAGCCTGGACGACATCGACCTGTCTGCCCTGCGGGACCCTGCAGGAA TCTTTGAGCTGGTGGAGGTGGTTGGCAATGGAACCTATGGACAGGTATACAAGGGGCGGCACGTCAAGAC TGGGCAGCTGGCTGCCATTAAGGTCATGGATGTCACAGAGGATGAGGAGGAAGAGATCAAACAGGAAATC AACATGTTAAAGAAGTACTCTCACCATCGCAATATTGCCACCTACTATGGGGCCTTTATCAAGAAGAGCC CTCCTGGGAACGATGACCAGCTCTGGCTGGTGATGGAGTTCTGCGGTGCTGGTTCAGTGACCGACCTGGT AAAGAACACAAAAGGGAACGCACTGAAGGAGGATTGCATTGCTTACATCTGCAGGGAGATTCTCAGGGGT CTTGCCCATCTCCATGCCCACAAGGTGATCCACAGAGATATCAAGGGACAAAATGTGCTGCTGACAGAGA ATGCTGAAGTCAAGCTAGTGGATTTTGGGGTGAGTGCTCAGCTGGACCGCACTGTGGGCAGGCGGAACAC TTTCATTGGAACCCCATACTGGATGGCTCCAGAAGTCATTGCCTGTGACGAGAACCCCGATGCCACCTAT GACTACAGGAGTGACATTTGGTCTCTAGGAATCACAGCCATTGAAATGGCAGAGGGAGCCCCCCCTCTGT GTGACATGCACCCTATGCGGGCCCTCTTCCTCATCCCTCGGAACCCTCCCCCCAGGCTCAAGTCAAAGAA ATGGTCTAAGAAGTTCACTGACTTCATCGACACGTGTCTCATCAAGACTTACCTGAGCCGCCCACCCACC GAACAGTTACTCAAATTCCCCTTCATCCGAGACCAGCCCACGGAGCGGCAGGTCCGCATCCAGCTCAAGG ACCACATCGACCGCTCGCGGAAGAAGCGGGGTGAGAAAGAGGAGACAGAGTATGAGTACAGCGGCAGTGA GGAGGAAGACGACAGCCATGGAGAGGAAGGCGAGCCAAGCTCCATCATGAATGTGCCCGGTGAGTCCACA CTGCGCAGAGAATTCCTCAGACTCCAGCAGGAGAATAAGAGCAACTCTGAGGCTTTAAAGCAGCAGCAGC AGCTGCAGCAACAGCAGCAGCGGGACCCGGAGGCACACATCAAACACCTGCTGCACCAGCGGCAGCGTCG CATAGAGGAGCAGAAGGAGGAGCGGCGACGTGTGGAGGAGCAACAGCGGCGAGAGCGAGAACAGCGTAAG CTACAAGAGAAGGAGCAGCAGCGGCGATTGGAAGACATGCAAGCCCTACGACGAGAGGAAGAGAGGCGGC AAGCAGAGCGGGAACAGGAATACAAGCGGAAGCAGCTGGAGGAGCAGCGGCAGTCAGAGCGGCTGCAGAG ACAGCTGCAGCAGGAGCACGCCTACCTCAAGTCCCTGCAGCAGCAGCAGCAGCAGCAGCAGCTCCAGAAG CAGCAGCAGCAGCAGCAGCAGATCCTGCCTGGAGACAGGAAGCCCCTGTATCATTACGGTCGGGGCATTA ATCCTGCTGACAAGCCAGCATGGGCCCGCGAGGTGGAAGAGAGAGCACGGATGAACAAGCAGCAGAACTC TCCCTTGGCGAAGGCGAAGCCAAGCAGTGCGGGGCCAGAGCCCCCCATCTCCCAGGCCTCTCCTAGCCCC CCAGGACCTCTTTCCCAGACTCCTCCTATGCAGAGGCCTGTGGAGCCCCAGGAAGGACCGCACAAGAGCC TGGTGGCACACCGGGTCCCACTGAAGCCATATGCAGCACCTGTACCCCGATCCCAGTCCCTGCAGGACCA GCCGACTCGAAACCTGGCTGCCTTCCCAGCCTCCCACGACCCTGACCCTGCTGCTGTCCCTACACCCACT GCCACACCCAGTGCCCGAGGAGCTGTCATCCGCCAGAATTCAGACCCCACCTCTGAAGGGCCAGGGCCTA GCCCAAACCCTCCATCCTGGGTTCGGCCTGATAATGAGGCTCCACCTAAGGTTCCACAGAGGACCTCTTC TATCGCCACTGCCCTTAACACCAGTGGGGCCGGAGGGTCCCGGCCAGCTCAGGCTGTCCGTGCCAGACCT CGCAGTAACTCCGCCTGGCAAATCTATCTGCAGAGGCGGGCAGAGCGGGGCACCCCCAAGCCTCCCGGGC CCCCAGCTCAGCCCCCTGGCCCGCCCAACGCCTCTAGTAACCCTGACCTCAGGAGGAGTGACCCTGGCTG GGAGCGCTCAGACAGTGTCCTCCCGGCCTCCCACGGCCACCTCCCTCAGGCTGGCTCCTTGGAGCGGAAC CGAAACCGTGTGGGAGCCTCCACAAAACTGGATAGCTCTCCAGTGCTCTCCCCTGGGAACAAAGCCAAGC CTGAAGACCACCGCTCAAGGCCAGGCCGGCCCGCAAGCTATAAGCGAGCAATTGGCGAGGACTTTGTGTT GCTCAAAGAGCGGACTCTGGATGAGGCCCCTAAGCCTCCCAAGAAGGCCATGGACTACTCCTCATCCAGT GAGGAGGTGGAAAGCAGTGAAGAGGAGGAGGAGGAAGGCGATGGGGAGCCGTCAGAGGGGAGCAGAGACA CTCCCGGGGGCCGTGATGGTGATACAGACAGCGTCAGCACCATGGTGGTTCATGATGTTGAGGAGATATC CGGGACCCAGCCCTCATATGGCGGCGGCACCATGGTGGTCCAGCGTACTCCTGAAGAGGAACGAAGCCTG CTGCTTGCTGATAGCAATGGCTACACAAACCTGCCTGATGTGGTCCAGCCCAGCCACTCACCTACTGAGA ACAGCAAAGGTCAAAGCCCTCCAACAAAGGATGGAGGCAGTGATTACCAGTCTCGTGGGCTGGTAAAGGC CCCAGGAAAGAGCTCATTCACCATGTTTGTGGATCTAGGGATCTACCAGCCTGGAGGCAGTGGGGACACC ATCCCTATCACAGCCCTAGTGGGTGGAGAAGGTGGTCGCCTTGATCAACTGCAGTTCGATGTGAGGAAGG GCTCTGTGGTCAACGTCAATCCCACCAACACCCGAGCTCATAGTGAAACTCCTGAAATTCGCAAGTACAA GAAGCGATTCAACTCAGAGATCCTATGTGCAGCTCTCTGGGGGGTCAACCTCCTAGTGGGCACAGAGAAT GGGCTGATGTTGCTGGACCGAAGTGGGCAGGGCAAGGTGTATGGACTTATTGGGCGACGACGCTTCCAGC AAATGGATGTCTTAGAAGGGCTCAACTTGCTCATCACCATCTCAGGGAAAAGGAACAAACTGCGGGTATA TTACCTGTCCTGGCTTCGGAACAAGATCCTACACAATGACCCAGAGGTGGAAAAGAAGCAGGGGTGGACC ACCGTGGGGGACATGGAGGGCTGCGGCCACTACCGTGTTGTGAAATATGAACGGATTAAGTTCCTGGTCA TTGCCCTGAAGAACTCCGTGGAGGTTTATGCCTGGGCTCCCAAACCCTACCACAAATTCATGGCCTTCAA GTCCTTTGCTGACCTCCCTCACCGCCCTCTACTGGTGGACCTGACAGTAGAGGAGGGACAGCGGCTCAAG GTCATCTATGGCTCCAGTGCTGGCTTCCATGCTGTGGATGTTGATTCTGGGAACAGCTATGACATCTACA TCCCTGTACATATCCAGAGCCAGATCACACCCCACGCCATCATCTTCCTCCCCAACACTGATGGCATGGA GATGCTGCTGTGCTATGAAGATGAGGGTGTCTATGTCAACACTTACGGGCGGATCATCAAGGATGTGGTG CTGCAGTGGGGAGAGATGCCCACCTCTGTGGCCTACATCTGCTCCAACCAGATAATGGGCTGGGGTGAGA AGGCCATAGAGATCCGCTCTGTGGAGACAGGCCACCTAGATGGGGTCTTCATGCACAAACGAGCCCAGAG GCTCAAGTTCCTGTGTGAGCGCAATGACAAGGTGTTTTTTGCCTCTGTCCGCTCTGGAGGAAGCAGCCAA GTTTACTTTATGACTCTGAACCGTAACTGCATCATGAACTGGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
Restriction Sites | SgfI-MluI |
ACCN | NM_001045964 |
Insert Size | 4035 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001045964.1, NP_001039429.1 |
RefSeq Size | 4994 bp |
RefSeq ORF | 4035 bp |
Locus ID | 50932 |
Gene Summary | Serine/threonine kinase which acts as a negative regulator of Ras-related Rap2-mediated signal transduction to control neuronal structure and AMPA receptor trafficking. Required for normal synaptic density, dendrite complexity, as well as surface AMPA receptor expression in hippocampal neurons. Can activate the JNK and MAPK14/p38 pathways and mediates stimulation of the stress-activated protein kinase MAPK14/p38 MAPK downstream of the Raf/ERK pathway. Phosphorylates: TANC1 upon stimulation by RAP2A, MBP and SMAD1. Has an essential function in negative selection of thymocytes, perhaps by coupling NCK1 to activation of JNK1.[UniProtKB/Swiss-Prot Function] |
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