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Tnr (NM_022312) Mouse Untagged Clone
CAT＃: MC224323
Tnr (untagged) - Mouse tenascin R (Tnr), (10ug)
CNY 17,390.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | J1-tenascin; janusin; restrictin; TN-R |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC224323 representing NM_022312
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGGATCGATGGGGAAACAGTAGTCTTGAAGAACATGCTCATTGGTGTAAACCTGATCCTGTTGGGAT CCATGCTCAAGCCTTCTGAGTGTCGGCTGGAGGTGACTACAGAAAGGGCTCAGAGACAAACTGTGGAGGA GGAAGGAGGGGCTTCCAGCTACAATACTTCCAGCAAGGAACAGCCTATGGTCTTCAACCATGTGTATAAC ATCAACGTGCCACTTGAAAGCCTCTGCTCCTCGGGGCTGGAGGCCTCAGCTGAGCAGGACATGAGTGCTG AAGATGATACTCTGGCCGAATACATAGGCCAAACCTCAGACCATGAAAGCCAGGTTACCTTCACCCACAA GATCAACCTCCCCAAAAAAGCCTGCCCATGTGCAAGCTCTTCCCAGGTACTGCAGGAACTGCTGAGCCGG ATCGAGATGCTGGAGAGGGAGGTGTCCTTGCTGCGAGACCAGTGCAATACCAACTGCTGTCAGGAAAGCG CTGCCACAGGACAACTGGACTATGTCCCTCACTGCAGCGGCCATGGCAACTTTAGCTTCGAGTCCTGTGG CTGCATCTGCAATGAAGGCTGGTTTGGCAAGAACTGCTCAGAGCCCTACTGCCCACTGGGCTGCTCCAGT CGGGGTGTGTGTGTCGATGGCCAGTGCATTTGTGACAGTGAATACAGCGGAGATGACTGTTCAGAGCTCC GGTGCCCAACAGACTGCAGTTCCCGAGGGCTCTGTGTGGATGGGGAATGTGTCTGTGAAGAGCCCTACAC AGGCGAGGACTGCAGGGAGCTGCGCTGCCCTGGGGACTGTTCAGGGAAGGGGCAATGTGCCAATGGTACC TGCCTGTGCCAAGAGGGCTATGCTGGTGAGGACTGCAGCCAGCGACGGTGTCTGAATGCCTGCAGTGGGC GAGGTCACTGCCAGGAGGGGCTCTGCATCTGTGAGGAAGGCTACCAGGGCCCTGACTGCTCAGCAGTTGC CCCTCCAGAGGACTTGCGAGTGGCTGGTATCAGCGACAGGTCCATTGAGCTGGAATGGGACGGGCCGATG GCAGTGACGGAATATGTGATCTCTTACCAGCCGACGGCCCTGGGGGGCCTTCAGCTCCAGCAGCGGGTGC CTGGAGATTGGAGTGGTGTCACCATCATGGAGCTGGAGCCAGGTCTCACCTACAACATCAGCGTCTACGC TGTCATTAGCAACATCCTCAGCCTTCCCATCACTGCCAAGGTGGCCACTCATCTCTCCACTCCTCAAGGG CTACAGTTCAAGACGATCACAGAGACCACCGTGGAGGTGCAGTGGGAGCCCTTCTCTTTCTCCTTCGACG GGTGGGAGATCAGCTTCATTCCAAAGAACAATGAAGGAGGGGTGATTGCTCAGCTCCCCAGCGATGTGAC GTCCTTTAACCAGACAGGACTGAAACCTGGGGAGGAGTACATTGTGAATGTTGTGGCTCTAAAGGAACAA GCCCGGAGCCCTCCTACCTCTGCCAGCGTCTCCACTGTCATTGACGGGCCCACACAGATCCTGGTTCGAG ATGTCTCTGATACTGTGGCTTTTGTGGAATGGACCCCACCTCGAGCCAAAGTTGATTTCATTCTTTTAAA ATATGGCTTGGTGGGTGGCGAAGGCGGGAAGACGACCTTCCGGCTGCAGCCTCCCTTAAGCCAGTACTCC GTGCAAGCCCTTAGACCTGGCTCGCGCTACGAGGTGTCCATCAGCGCAGTCCGGGGGACCAATGAGAGTG AAGCCTCAAGCACCCAATTTACAACAGAGATTGATGCTCCCAAGAATTTGCGAGTGGGTTCCCGCACAGC AACTAGCCTTGACCTGGAATGGGATAACAGCGAGGCCGAAGCTCAGGAGTACAAGGTTGTGTACAGCACC TTAGCTGGTGAACAGTACCACGAAGTGCTGGTACCCAAGGGCATTGGCCCAACTACCAAGACTACCCTCA CAGATCTGGTTCCAGGCACAGAGTATGGAGTTGGAATATCTGCAGTAATGAACTCAAAACAAAGCATTCC TGCCACTATGAATGCCAGGACTGAACTTGACAGTCCCCGAGACCTCATGGTAACAGCCTCCTCAGAGACC TCTATCTCTCTCATCTGGACCAAGGCCAGTGGTCCCATTGATCACTACAGAATTACTTTTACCCCATCTT CTGGGATCTCCTCCGAAGTCACTGTGCCCAGGGATAGGACTTCATACACACTAACAGATCTAGAGCCTGG AGCAGAATACATTATCTCCATCACTGCTGAGAGGGGTCGGCAGCAGAGCCTGGAGTCTACTGTGGATGCC TTCACAGGCTTCCGCCCTATCTCCCATTTGCACTTTTCTCATGTGACCTCCTCCAGTGTCAATATCACCT GGAGTGACCCATCTCCCCCAGCAGACAGACTCATTCTGAACTACAGCCCCAGGGACAAAGAGGAAGACAT GTTGGAGGTCCTCTTGGATGCCACCAAGAGGCACGCTGTCTTGATGGGTCTACAGCCAGCCACTGAATAT ATAGTGAACCTTGTAGCTGTCCATGGGACGGTAACCTCTGAACCCATAGTGGGTTCTATCACTACAGGAA TTGATCCTCCCAAAAACATCACAATTAGCAACGTGACTAAGGACTCCCTGACGGTGTCCTGGAGCTCTCC TGTTGCGCCTTTTGATTACTACCGAGTATCGTACCGACCCACCCAAGTGGGACGGCTAGACAGCTCCGTA GTGCCCAACACCGTGACAGAGTTCGCCATCACCAGGCTGTATCCAGCTACTGAATATGAAATAAGCCTCA ACAGTGTACGGGGCAGGGAGGAGAGTGAACGCATCTGCACCCTGGTGCACACAGCCATGGATAGCCCCAT GGATTTGATCGCTACCAACATCACACCTACAGAAGCCTTGCTCCAGTGGAAAGCACCCATGGGTGAAGTG GAAAATTATGTCATCGTCCTCACACACTTTGCAATTGCTGGAGAGACCATCCTGGTTGACGGGGTCAGCG AAGAATTCCAGCTTGTAGACTTGCTTCCTAGCACCCACTACACTGTCACTATGTATGCCACCAGTGGGCC TCTCATGAGTGGCACCATTGCCACCAACTTCTCCACCCTCCTGGACCCTCCTGACAACCTGACAGCCAGT GAAGTCACCAGGCAAAGCGCACTGATCTCCTGGCAGCCGCCCAGAGCTGCGATTGAAAACTATGTCTTGA CATACAAGTCCACCGATGGAAGCCGCAAAGAGCTGATAGTGGATGCTGAGGACACCTGGATCCGACTAGA GGGCCTGTCAGAGAACACAGACTACACAGTGCTCCTGCAGGCAGCCCAGGAGGCCACAAGGAGCAGTCTC ACCTCTACTGTCTTTACCACAGGGGGCCGGGTGTTCTCTCATCCTCAAGACTGTGCCCAGCATTTGATGA ATGGAGACACTCTGAGTGGCGTTTACACCATCTTCCTCAATGGGGAGCTAAGCCACAAGCTGCAAGTGTA CTGTGACATGACCACAGATGGGGGCGGCTGGATTGTATTCCAGAGGCGGCAAAATGGACAAACTGATTTT TTCCGGAAATGGGCAGATTATCGTGTTGGCTTTGGGAATCTGGAGGATGAGTTTTGGCTAGGGCTAGACA ACATCCACAGGATAACAGCCCAGGGCCGCTATGAGCTGCGTGTGGATATGCGGGATGGACAGGAAGCAGT CTTTGCCTACTATGACAAGTTCGCTGTGGAGGACAGCAGAAGCCTGTACAAGATCCGCATAGGAAGTTAC AATGGCACTGCAGGAGACTCCCTCAGCTATCACCAGGGACGTCCTTTCTCCACTGAGGACAGAGACAATG ATGTTGCAGTCACCAACTGTGCCATGTCCTACAAGGGTGCTTGGTGGTATAAGAACTGCCACCGGACCAA CCTCAACGGGAAGTACGGGGAGTCCAGGCACAGTCAGGGGATCAACTGGTACCATTGGAAAGGCCATGAA TTCTCCATCCCCTTTGTAGAAATGAAGATGAGGCCCTACATCCATCGTCTCACAGCCGGGAGGAAACGGC GAGCCTTGAAATTCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_022312 |
| Insert Size | 4077 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_022312.3, NP_071707.2 |
| RefSeq Size | 5395 bp |
| RefSeq ORF | 4077 bp |
| Locus ID | 21960 |
| UniProt ID | Q8BYI9 |
| Gene Summary | Neural extracellular matrix (ECM) protein involved in interactions with different cells and matrix components. Theses interactions can influence cellular behavior by either evoking a stable adhesion and differentiation, or repulsion and inhibition of neurite growth. Binding to cell surface gangliosides inhibits RGD-dependent integrin-mediated cell adhesion and results in an inhibition of PTK2/FAK1 (FAK) phosphorylation and cell detachment. Binding to membrane surface sulfatides results in a oligodendrocyte adhesion and differentiation. Interaction with CNTN1 induces a repulsion of neurons and an inhibition of neurite outgrowth. Interacts with SCN2B may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier. TNR-linked chondroitin sulfate glycosaminoglycans are involved in the interaction with FN1 and mediates inhibition of cell adhesion and neurite outgrowth. The highly regulated addition of sulfated carbohydrate structure may modulate the adhesive properties of TNR over the course of development and during synapse maintenance (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG225166 | Tnr (tGFP-tagged) - Mouse tenascin R (Tnr), (10ug) |
CNY 11,880.00 |
|
| MR225166 | Tnr (Myc-DDK-tagged) - Mouse tenascin R (Tnr) |
CNY 9,296.00 |
|
| MR225166L3 | Lenti ORF clone of Tnr (Myc-DDK-tagged) - Mouse tenascin R (Tnr) |
CNY 12,730.00 |
|
| MR225166L4 | Lenti ORF clone of Tnr (mGFP-tagged) - Mouse tenascin R (Tnr) |
CNY 12,730.00 |
