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Arhgef5 (NM_133674) Mouse Untagged Clone
CAT＃: MC224710
Arhgef5 (untagged) - Mouse Rho guanine nucleotide exchange factor (GEF) 5 (Arhgef5), (10ug)
CNY 20,330.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 2210412D05Rik; AA717842; AW495314; Tim1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC224710 representing NM_133674
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAGGCTGAGGAGCCTGAATATGGAGTATCTACAGAAGTCCCTGACATAGAAGAATTGAAAACTATCC CTGAAGGTATCATGAGGAGCAGTCAGATCCCTGCCTTGGATCCTGAAGCTCAAGAAGACCGAGACCCATC CTATAAGTGGACAGATGGACACAGACCCGTGATGAACCAGTCAAAAGTGTTAAGGGACATGGGTGACCAT ACACCTAATAGTATGGCAATTTTCTTCAAGAAAGAATCTTCGGATATGGAGACAAGCCAGGAAATCCTTC TGGCTGAGGCCTGTAACACTCCAGACCAGCAGGAAGCTGTAATCCAGAGCCTTAAAGACAGACTGTCAAG AACAATAGCTGCCCCTGAGCTCTTGGCATGTGCTGTCCAGGAAGAATGGCTAGACATACCCAGCAAACTA GACAACAGAGTGGGGGCAGAATTGCAGTCAGAACTTATGTCTTTGACTTTGGCAGTTAGCAAAGAGAAAG AAGAGGAAGAAACCTCCCCAGACACCTCAATCCCTAGAGGATCTTGGCCTCCCTGCAAAACTCACCCTGG TGAGACTGAGCAGACCCAGGGCAGTGGAAGTGAACTGCTTAGGCAGGGGAAACAGCTGCAGTTGGAGGCC ACACAAGAAAATCAAGGGCAAGAAGGCTTCCTTCAATCTCAGGAAGCCCAGGGACTGGAGGAGCAGGAGG GACAGGAAGTAGAAATTCAGGAGGAAGGAACTCTGAACGAAGGCATTTGTTTTGGTGGGCTCCTGGGAGA GCAGGAGGAGGTGGAAGAGGGGTTTAACGGCAACGAGGAAGAACAGAAGCAGGGACAGATCCAAAGCTAT ATGCTACTTGGAGGACAATGGGAAAATGAGGGGCTCAGTGGGGAATTAGAAGGTCTGAATTACAGTGAGA GAGGCCAAGAGAACAGGGAAAGGAGGGTTTGGGTTCTGAGAGATTCAGAAGAGGAGGGACAGGACCAGGA ATCCAGGGAGGTGGAAGAGAGAAGGGTAGCCACTCAGTATACAGAGAATCAAAGGTTAGTAGAGAAATCA GAGATTGTAAAGAGAAAGCAGAGAGATCATGATCAAACAGGAAAAGTGATGCCCGTAAGGGACCAGAAGG AGGTTGTAGACTCAGGTGACAGGGTCCAAGGGAATGGGGATAGTGGTGGGCAGACAGCAGTGGAAGGGAG CAGACCAGGAGAGGACAGCAAGCCTTCTCTTCCAGTGGCTTCCGTAGATCCTGAGGTTCTCTCCCCAGGT ACATTGTTCCCAGGTATTTCTTCCTCTGTGGCTGATATTCCACAGATTCAGAAGGAGCCTGTGTGTGAGG AACTGAGCCCTCAAGCTCCTGCACTGGAGCCAACAGAATGGTCTCACCAACCCATTTCTCCCCCTGCCTC TTTTGCTCCTGAAGAATCTCTTGATAATAGGACTCACAACAGCCAGCAAGAAGAATTCAGGCTAAGGAAG GGGATTGAGGTTGTCTCTGCTAGTACATCTGTGGCTCCTTCAGGGACACGAGATTCACCTCCTTTCAGTC CTCCTAATGTTTTCTCCAGCACTGCCACCTTGTCACCTGTTAGCTCTTCAGTTATCCTTCCTGAGGAGAC CCCAACAGCCTCTGCCTCAGCTGACACTCCACATCATTGTGGGCCATGTGAGACTCCTCCACTACCCGCA AAATCCTCCAGGTACCCATGTGCCACCTCTGACACAGCCAACCCTCACAGCCCTCTTAGCAGCTACACTG GAGTTACCCAACATCTAAGAAGCAACTCGTTCCCAGGCTCTCACAGGACAGAGCAGACTCCAGACTCTCT GGGAATGTCACTCTCTTTCTCTCATTTGGAATTACCTCAGAGGCCTCCTAAACCAGCCATCTATGGCTCT CTGACCCCAAGAAGAAACAGAAGAAGTAGGGATGGTATCGTCTTTTCAGACTCCTCTACTGCTTTGTTTG CTTTGAAACAGGACTCTGAAGAATTCACTTCAAATCCAGAGAGGCCCAGCAGTCCTCATGGTAGTCCGAC ATGGGGCTCCCCACAGAACTCAGCCTTTGCCATAGGCTCTCCTGCAAATGTTTCTTCACCACCCACTGTC TCCATGGATATGACGATACGTGAAGCTTTACTCCCTATTCCCCCAGAGAAGAGACATAGCTACAGTCACA TAGTGGAGAGGGATGGCCTTCTTCATGAAGTAGCCTCTACACTGAAGCGGCATAGTCATCCTCCTCCACT GACCCTAAGTTCAGGGCTCCATAGATCTTCTAAAGGCTCATTTTCCCTAGTTCCTGACTCCACTGTGGCA AGGCAGCACCGCCCTCTGCCGTCTACCCCAGAAAGCCCCAACCATACACAGACCTCCATCCCTTCCAGAC TGAGATACAACAAACCATTACCCCCAACTCCTGATATGCCTGAGTTCTACCATCCCTCCATCTCTTCCTC TTATATCTCAAGGATGTATAGGCCTCTACCCCCAGTCCCTATCATAGATCCTTCCTCTGAACCACCTCCA TTGCCCCCAAAGTCCAGGGGGAGAAGCAAGAGTATCCAGGGAGGAGTTATACATTCAGGAGGTCAAGCCA AGCCAAGACCTAATAATCAAGACTGGACAGCTTCTACTCTCTCTGTTGGACGAACCTCCTGGCCTCCAGC CACAGGCAGATCAACAGAATCTTTGCCTCTCACCAGTAGGTGTAATAATGAAGTGTCCCCTGGCCTGGCT TTCAGCAACATGACAAACCTTCTTAGTCCCTCTTCTCCTACTACTCCTTGGATCCCAGACCTTCAGAGAC CTACCACTAAGGATGAGTCAGGGCTCACTGAAGAGTCTGAGCCACCAGTGAGAGGATCATTTAGACGATC TGCCCCTCAGGAGGAATTTAATAATACAAGGAGGTCAGCTTTAGGATCAAGAAAGAACTCAGAAAAACCC CTCCACCACCAACTGGAGAAGGCATCCAGCTGGCCTCACAGACGCGACCCAGCAAGGACATCAGAAAGTA GCAGTGAACAGGTTGTTCTGGGCCAGGTACCCAACAAGCAAAAGGGCTGGAACCGGCAAGGCCTTCGTAG ACCTTCAATTTTGCCTGAAAGCTCTTCAGATTTACGAAATCCAGCTGCGGGAAGACTTCCTGGCTCTTCA GATTCTGTTGTTTTCCGGGAGAAGAAACCAAAGGAGGGGATGGGAGGCTTTTCAAGACGTTGCTCCAAGC TCATCTCCTCCCAGCTACTTTATCAGGAGTACAGTGATGTTGTTCTGAACAAGGAGATTCAGAGCCAGCA GCGGCTGGACAGCCTGGCCGAGCCACATGGGCTCTCTTCCCCACGGCATCGTCGAAAGGCACTGGTCTCT TCAGACTCCTACCTACAGCGCCTCTCTATGGCCTCCAGTGGCTCCCTCTGGCAGGAAATCCCTGTGGTGC GCAATAGCACAGTGCTGCTCTCCATGACCCATGAAGATCAAAAACTGCAAGAGGCCAAGTTTGAGCTGAT TGTGTCAGAAGCATCTTACCTGCGCAGTCTAAACATAGCTGTGGATCATTTCCAACATTCAGCCCAGCTG CGGGGCACCCTGTCCAACCAGGATCATCAGTGGCTCTTCTCTCGTTTGCAGGATGTACGAGATGTCAGCA CCACGTTCCTTTCAGACCTAGAAGAAAACTTTGAGAACAACATCTTCTCCTTCCAAGTGTGTGATGTTGT CTTGAATCATGCCGCAGACTTCCACCGTGTCTACCTGCCTTATGTCACCAACCAGACCTATCAGGAACGC ACCTTCCAAAGTCTAATGAATAGCAACAGCAGTTTCCGGGAGGTCTTGGAGAAGCTAGAGAGCGACCCCA TCTGCCAACGCCTGTCTCTCAAGTCCTTTCTGATACTGCCCTTCCAACGCATCACACGTCTCAAGCTGCT GCTCCAGAACATACTGAAGAGAACTCAGCCTGGCTCCTCAGAAGAGGCAGAGGCCACGAAGGCACACCAT GCCCTAGAGAAGCTGATTCGAGACTGCAACAGCAATGTGCAGAGAATGCGGCGGACAGAGGAGCTCATCT ACCTGAGCCAGAAGATTGAGTTTGAGTGCAAAATTTTCCCACTTATTTCACAATCTCGATGGCTGGTGAA GAGTGGGGAGCTGACGGCCCTTGAGTTCAGTGTCTCCCCAGGGCTGAGAAGGAAACTGACCACTCGTCCA GTCCACCTACATCTCTTCAATGACTGTCTGTTGCTGTCTCGGCCCCGAGAGGGCAGCCGGTTCCTGGTAT TTGACCATGCTCCGTTCTCCTCCATCCGAGGGGAGAAGTGTGAAATGAAGCTTCATGGACCTCACAAAAA CCTCTTCCGTCTCTTTCTCCTGCACAACGCACAGGGCACCCAAGTGGAATTCCTCTTCCGCACTGAGACT CAAAGTGAAAAGCTTCGCTGGATCTCAGCCTTGGCCATGCCCAGAGAGGAGTTGGACCTCCTTGAGTGTT ATGACTCCCCACAAGTTCAGTGCCTCCGTGCCTACAAGCCTCGAGAGAATGATGAGTTGGCACTAGAGAA GGCGGATGTGGTGATGGTCACTCAGCAAAGCAGTGATGGCTGGCTGGAGGGTGTAAGACTCTCAGATGGT GAGCAAGGCTGGTTTCCTGTCCAGCAGGTAGAGTTCATTTCAAACCCAGAGGTCCGTGCTCAGAACCTCA AGGAAGCCCATCGAGTCAAGACGGCCAAACTGCAGCTGGTAGAACAGCAAGTCTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_133674 |
| Insert Size | 4746 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_133674.1, NP_598435.1 |
| RefSeq Size | 5420 bp |
| RefSeq ORF | 4746 bp |
| Locus ID | 54324 |
| UniProt ID | E9Q7D5 |
| Gene Summary | Guanine nucleotide exchange factor which activates Rho GTPases (PubMed:19713215, PubMed:21525037). Strongly activates RHOA (PubMed:19713215, PubMed:21525037). Also strongly activates RHOB, weakly activates RHOC and RHOG and shows no effect on RHOD, RHOV, RHOQ or RAC1 (PubMed:19713215). Involved in regulation of cell shape and actin cytoskeletal organization (PubMed:21525037). Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia (By similarity). Required for SRC-induced podosome formation (PubMed:21525037). Involved in positive regulation of immature dendritic cell migration (PubMed:19713215).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG215297 | Arhgef5 (tGFP-tagged) - Mouse Rho guanine nucleotide exchange factor (GEF) 5 (Arhgef5), (10ug) |
CNY 13,300.00 |
|
| MR215297 | Arhgef5 (Myc-DDK-tagged) - Mouse Rho guanine nucleotide exchange factor (GEF) 5 (Arhgef5) |
CNY 17,304.00 |
|
| MR215297L1 | Lenti ORF clone of Arhgef5 (Myc-DDK-tagged) - Mouse Rho guanine nucleotide exchange factor (GEF) 5 (Arhgef5) |
CNY 13,970.00 |
|
| MR215297L2 | Lenti ORF clone of Arhgef5 (mGFP-tagged) - Mouse Rho guanine nucleotide exchange factor (GEF) 5 (Arhgef5) |
CNY 19,704.00 |
|
| MR215297L3 | Lenti ORF clone of Arhgef5 (Myc-DDK-tagged) - Mouse Rho guanine nucleotide exchange factor (GEF) 5 (Arhgef5) |
CNY 13,970.00 |
|
| MR215297L4 | Lenti ORF clone of Arhgef5 (mGFP-tagged) - Mouse Rho guanine nucleotide exchange factor (GEF) 5 (Arhgef5) |
CNY 13,970.00 |
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