Tor1a (NM_144884) Mouse Tagged Lenti ORF Clone
CAT#: MR204930L3
- LentiORF®
Lenti ORF clone of Tor1a (Myc-DDK-tagged) - Mouse torsin family 1, member A (torsin A) (Tor1a)
"NM_144884" in other vectors (4)
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CNY 4,750.00
CNY 600.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | DQ2; Dyt1; torsinA |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR204930).
|
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_144884 |
ORF Size | 1002 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_144884.1 |
RefSeq Size | 1452 bp |
RefSeq ORF | 1002 bp |
Locus ID | 30931 |
UniProt ID | Q9ER39 |
Gene Summary | Protein with chaperone functions important for the control of protein folding, processing, stability and localization as well as for the reduction of misfolded protein aggregates. Involved in the regulation of synaptic vesicle recycling, controls STON2 protein stability in collaboration with the COP9 signalosome complex (CSN). In the nucleus, may link the cytoskeleton with the nuclear envelope, this mechanism seems to be crucial for the control of nuclear polarity, cell movement and, specifically in neurons, nuclear envelope integrity. Participates in the cellular trafficking and may regulate the subcellular location of multipass membrane proteins such as the dopamine transporter SLC6A3, leading to the modulation of dopamine neurotransmission. In the endoplasmic reticulum, plays a role in the quality control of protein folding by increasing clearance of misfolded proteins such as SGCE variants or holding them in an intermediate state for proper refolding. May have a redundant function with TOR1B in non-neural tissues.[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC201138 | Tor1a (untagged) - Mouse torsin family 1, member A (torsin A) (Tor1a), (10ug) |
CNY 3,656.00 |
|
MG204930 | Tor1a (tGFP-tagged) - Mouse torsin family 1, member A (torsin A) (Tor1a) |
CNY 3,140.00 |
|
MR204930 | Tor1a (Myc-DDK-tagged) - Mouse torsin family 1, member A (torsin A) (Tor1a) |
CNY 3,656.00 |
|
MR204930L4 | Lenti ORF clone of Tor1a (mGFP-tagged) - Mouse torsin family 1, member A (torsin A) (Tor1a) |
CNY 4,750.00 |