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Tor1a (NM_144884) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR204930L3V
- LentiORF®
-
Lenti ORF particles, Tor1a (Myc-DDK-tagged) - Mouse torsin family 1, member A (torsin A) (Tor1a), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | Tor1a (NM_144884) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | DQ2; Dyt1; torsinA |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_144884 |
| ORF Size | 1002 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR204930).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_144884.1 |
| RefSeq Size | 1452 bp |
| RefSeq ORF | 1002 bp |
| Locus ID | 30931 |
| Gene Summary | Protein with chaperone functions important for the control of protein folding, processing, stability and localization as well as for the reduction of misfolded protein aggregates. Involved in the regulation of synaptic vesicle recycling, controls STON2 protein stability in collaboration with the COP9 signalosome complex (CSN). In the nucleus, may link the cytoskeleton with the nuclear envelope, this mechanism seems to be crucial for the control of nuclear polarity, cell movement and, specifically in neurons, nuclear envelope integrity. Participates in the cellular trafficking and may regulate the subcellular location of multipass membrane proteins such as the dopamine transporter SLC6A3, leading to the modulation of dopamine neurotransmission. In the endoplasmic reticulum, plays a role in the quality control of protein folding by increasing clearance of misfolded proteins such as SGCE variants or holding them in an intermediate state for proper refolding. May have a redundant function with TOR1B in non-neural tissues.[UniProtKB/Swiss-Prot Function] |
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