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Cyfip1 (NM_011370) Mouse Tagged Lenti ORF Clone
CAT＃: MR222937L4
- LentiORF®
Lenti ORF clone of Cyfip1 (mGFP-tagged) - Mouse cytoplasmic FMR1 interacting protein 1 (Cyfip1), transcript variant 2
"NM_011370" in other vectors (3)
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CNY 14,440.00
Product images
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | mGFP |
| Synonyms | E030028J09Rik; l(7)1Rl; l7Rl1; l71Rl; mKIAA0068; P140SRA-1; P140sra1; pl-1; Shyc; Sra-1; Sra1 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| E. coli Selection | Chloramphenicol (34 ug/mL) |
| Mammalian Cell Selection | Puromycin |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR222937).
|
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_011370 |
| ORF Size | 3759 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_011370.3, NP_035500.2 |
| RefSeq Size | 6471 bp |
| RefSeq ORF | 3762 bp |
| Locus ID | 20430 |
| UniProt ID | Q7TMB8 |
| Gene Summary | Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. May act as an invasion suppressor in cancers. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (PubMed:27605705).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG222937 | Cyfip1 (tGFP-tagged) - Mouse cytoplasmic FMR1 interacting protein 1 (Cyfip1) transcript variant 2, (10ug) |
CNY 13,780.00 |
|
| MR222937 | Cyfip1 (Myc-DDK-tagged) - Mouse cytoplasmic FMR1 interacting protein 1 (Cyfip1), transcript variant 2 |
CNY 12,540.00 |
|
| MR222937L3 | Lenti ORF clone of Cyfip1 (Myc-DDK-tagged) - Mouse cytoplasmic FMR1 interacting protein 1 (Cyfip1), transcript variant 2 |
CNY 14,440.00 |
