Cyfip1 (NM_011370) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR222937L4V
- LentiORF®
Lenti ORF particles, Cyfip1 (GFP-tagged) - Mouse cytoplasmic FMR1 interacting protein 1 (Cyfip1), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 20,045.00
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Specifications
Product Data | |
Product Name | Cyfip1 (NM_011370) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | E030028J09Rik; l(7)1Rl; l7Rl1; l71Rl; mKIAA0068; P140SRA-1; P140sra1; pl-1; Shyc; Sra-1; Sra1 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_011370 |
ORF Size | 3759 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR222937).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_011370.3, NP_035500.2 |
RefSeq Size | 6471 bp |
RefSeq ORF | 3762 bp |
Locus ID | 20430 |
Gene Summary | Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. May act as an invasion suppressor in cancers. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (PubMed:27605705).[UniProtKB/Swiss-Prot Function] |
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