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LOX 1 (OLR1) (NM_002543) Human Tagged ORF Clone
CAT＃: RC204704
OLR1 (Myc-DDK-tagged)-Human oxidized low density lipoprotein (lectin-like) receptor 1 (OLR1), transcript variant 1
ORF Plasmid: tGFP
"NM_002543" in other vectors (7)
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CNY 2,400.00
CNY 3,990.00
| Cited in 1 publication. |
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | CLEC8A; LOX1; LOXIN; SCARE1; SLOX1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC204704 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGACTTTTGATGACCTAAAGATCCAGACTGTGAAGGACCAGCCTGATGAGAAGTCAAATGGAAAAAAAG CTAAAGGTCTTCAGTTTCTTTACTCTCCATGGTGGTGCCTGGCTGCTGCGACTCTAGGGGTCCTTTGCCT GGGATTAGTAGTGACCATTATGGTGCTGGGCATGCAATTATCCCAGGTGTCTGACCTCCTAACACAAGAG CAAGCAAACCTAACTCACCAGAAAAAGAAACTGGAGGGACAGATCTCAGCCCGGCAACAAGCAGAAGAAG CTTCACAGGAGTCAGAAAACGAACTCAAGGAAATGATAGAAACCCTTGCTCGGAAGCTGAATGAGAAATC CAAAGAGCAAATGGAACTTCACCACCAGAATCTGAATCTCCAAGAAACACTGAAGAGAGTAGCAAATTGT TCAGCTCCTTGTCCGCAAGACTGGATCTGGCATGGAGAAAACTGTTACCTATTTTCCTCGGGCTCATTTA ACTGGGAAAAGAGCCAAGAGAAGTGCTTGTCTTTGGATGCCAAGTTGCTGAAAATTAATAGCACAGCTGA TCTGGACTTCATCCAGCAAGCAATTTCCTATTCCAGTTTTCCATTCTGGATGGGGCTGTCTCGGAGGAAC CCCAGCTACCCATGGCTCTGGGAGGACGGTTCTCCTTTGATGCCCCACTTATTTAGAGTCCGAGGCGCTG TCTCCCAGACATACCCTTCAGGTACCTGTGCATATATACAACGAGGAGCTGTTTATGCGGAAAACTGCAT TTTAGCTGCCTTCAGTATATGTCAGAAGAAGGCAAACCTAAGAGCACAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC204704 protein sequence
Red=Cloning site Green=Tags(s) MTFDDLKIQTVKDQPDEKSNGKKAKGLQFLYSPWWCLAAATLGVLCLGLVVTIMVLGMQLSQVSDLLTQE QANLTHQKKKLEGQISARQQAEEASQESENELKEMIETLARKLNEKSKEQMELHHQNLNLQETLKRVANC SAPCPQDWIWHGENCYLFSSGSFNWEKSQEKCLSLDAKLLKINSTADLDFIQQAISYSSFPFWMGLSRRN PSYPWLWEDGSPLMPHLFRVRGAVSQTYPSGTCAYIQRGAVYAENCILAAFSICQKKANLRAQ TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_002543 |
| ORF Size | 819 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_002543.4 |
| RefSeq Size | 2533 bp |
| RefSeq ORF | 822 bp |
| Locus ID | 4973 |
| UniProt ID | P78380 |
| Domains | CLECT |
| Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
| Protein Pathways | PPAR signaling pathway |
| MW | 31 kDa |
| Gene Summary | This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Deleterious role of endothelial lectin-like oxidized low-density lipoprotein receptor-1 in ischaemia/reperfusion cerebral injury
,Akhmedov, A;Bonetti, NR;Reiner, MF;Spescha, RD;Amstalden, H;Merlini, M;Gaul, DS;Diaz-Cañestro, C;Spescha, RS;Semerano, A;Giacalone, G;Savarese, G;Montecucco, F;Kulic, L;Nitsch, RM;Matter, CM;Kullak-Ublick, GA;Sessa, M;Lüscher, TF;Beer, JH;Liberale, L;Camici, GG;,
J. Cereb. Blood Flow Metab.
,PubMed ID 30073881
[LOX 1]
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Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204704L1 | Lenti ORF clone of Human oxidized low density lipoprotein (lectin-like) receptor 1 (OLR1), transcript variant 1, Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC204704L2 | Lenti ORF clone of Human oxidized low density lipoprotein (lectin-like) receptor 1 (OLR1), transcript variant 1, mGFP tagged |
CNY 4,800.00 |
|
| RC204704L3 | Lenti ORF clone of Human oxidized low density lipoprotein (lectin-like) receptor 1 (OLR1), transcript variant 1, Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC204704L4 | Lenti ORF clone of Human oxidized low density lipoprotein (lectin-like) receptor 1 (OLR1), transcript variant 1, mGFP tagged |
CNY 4,800.00 |
|
| RG204704 | OLR1 (tGFP-tagged) - Human oxidized low density lipoprotein (lectin-like) receptor 1 (OLR1), transcript variant 1 |
CNY 4,000.00 |
|
| SC118589 | OLR1 (untagged)-Human oxidized low density lipoprotein (lectin-like) receptor 1 (OLR1), transcript variant 1 |
CNY 2,400.00 |
|
| SC321097 | OLR1 (untagged)-Human oxidized low density lipoprotein (lectin-like) receptor 1 (OLR1), transcript variant 1 |
CNY 2,400.00 |
