Mknk2 (NM_001011985) Rat Tagged Lenti ORF Clone
CAT#: RR204301L4
- LentiORF®
Lenti ORF clone of Mknk2 (mGFP-tagged ORF) - Rat MAP kinase-interacting serine/threonine kinase 2 (Mknk2), (10 ug)
"NM_001011985" in other vectors (3)
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CNY 8,550.00
Specifications
Product Data | |
Type | Rat Tagged ORF Clone |
Tag | mGFP |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RR204301).
|
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_001011985 |
ORF Size | 1377 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001011985.1, NP_001011985.1 |
RefSeq Size | 3458 bp |
RefSeq ORF | 1380 bp |
Locus ID | 299618 |
UniProt ID | Q5U2N4 |
Gene Summary | Serine/threonine-protein kinase that phosphorylates SFPQ/PSF, HNRNPA1 and EIF4E. May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap. Required for mediating PP2A-inhibition-induced EIF4E phosphorylation. Triggers EIF4E shuttling from cytoplasm to nucleus. Enhances the formation of EIF4F complex in pachytene spermatocytes, thus promoting mRNA translation during spermatogenesis. Displays a high basal kinase activity. Acts as a mediator of the suppressive effects of IFNgamma on hematopoiesis. Negative regulator for signals that control generation of arsenic trioxide As(2)O(3)-dependent apoptosis and anti-leukemic responses. Involved in anti-apoptotic signaling in response to serum withdrawal (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RN204301 | Mknk2 (untagged ORF) - Rat MAP kinase-interacting serine/threonine kinase 2 (Mknk2), (10 ug) |
CNY 5,990.00 |
|
RR204301 | Mknk2 (Myc-DDK-tagged ORF) - Rat MAP kinase-interacting serine/threonine kinase 2 (Mknk2), (10 ug) |
CNY 5,990.00 |
|
RR204301L3 | Lenti ORF clone of Mknk2 (Myc-DDK-tagged ORF) - Rat MAP kinase-interacting serine/threonine kinase 2 (Mknk2), (10 ug) |
CNY 7,790.00 |