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Mknk2 (NM_001011985) Rat Tagged ORF Clone Lentiviral Particle
CAT＃: RR204301L4V
- LentiORF®
-
Lenti ORF particles, Mknk2 (GFP-tagged ORF) - Rat MAP kinase-interacting serine/threonine kinase 2 (Mknk2), 200ul, >10^7 TU/mL
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CNY 10,070.00
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Specifications
| Product Data | |
| Product Name | Mknk2 (NM_001011985) Rat Tagged ORF Clone Lentiviral Particle |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_001011985 |
| ORF Size | 1377 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RR204301).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001011985.1, NP_001011985.1 |
| RefSeq Size | 3458 bp |
| RefSeq ORF | 1380 bp |
| Locus ID | 299618 |
| Gene Summary | Serine/threonine-protein kinase that phosphorylates SFPQ/PSF, HNRNPA1 and EIF4E. May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap. Required for mediating PP2A-inhibition-induced EIF4E phosphorylation. Triggers EIF4E shuttling from cytoplasm to nucleus. Enhances the formation of EIF4F complex in pachytene spermatocytes, thus promoting mRNA translation during spermatogenesis. Displays a high basal kinase activity. Acts as a mediator of the suppressive effects of IFNgamma on hematopoiesis. Negative regulator for signals that control generation of arsenic trioxide As(2)O(3)-dependent apoptosis and anti-leukemic responses. Involved in anti-apoptotic signaling in response to serum withdrawal (By similarity).[UniProtKB/Swiss-Prot Function] |
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