LRRC25 (NM_145256) Human Untagged Clone

CAT#: SC100131

LRRC25 (untagged)-Human leucine rich repeat containing 25 (LRRC25)



  "NM_145256" in other vectors (5)

CNY 1,200.00

CNY 2,950.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (4)
LRRC25 mouse monoclonal antibody, clone OTI1D9 (formerly 1D9)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms MAPA
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC100131 sequence for NM_145256 edited (data generated by NextGen Sequencing)
ATGGGGGGCACCCTGGCATGGACGCTGCTGTTGCCGCTGCTGCTGCGGGAGTCAGACAGC
CTAGAACCGTCGTGCACCGTGTCCTCCGCGGATGTGGACTGGAACGCGGAGTTCAGTGCC
ACGTGCCTGAATTTCAGTGGCCTCAGCCTGAGCCTGCCTCACAACCAGTCTCTGCGGGCC
AGCAACGTGATTCTCCTTGACCTGTCTGGGAACGGCCTGCGAGAGCTTCCAGTGACCTTC
TTTGCCCACCTGCAGAAGCTTGAGGTCCTGAACGTGCTACGCAACCCCTTGTCTCGTGTG
GATGGGGCGCTGGCCGCCCGCTGTGACCTTGACCTGCAGGCCGACTGCAACTGTGCCCTG
GAGTCCTGGCACGACATCCGCCGAGACAACTGCTCTGGCCAGAAGCCTCTGCTCTGCTGG
GACACAACCAGCTCCCAGCACAACCTCTCTGCCTTCCTGGAGGTCAGCTGCGCCCCTGGC
CTGGCCTCTGCAACTATCGGGGCAGTGGTGGTCAGCGGGTGCCTGCTTCTTGGACTTGCC
ATCGCTGGCCCTGTGCTGGCCTGGAGACTCTGGCGATGCCGAGTGGCCAGAAGCCGGGAG
CTGAACAAACCCTGGGCTGCTCAGGATGGGCCCAAGCCCGGTTTAGGCTTGCAGCCACGG
TACGGCAGCCGGAGCGCCCCCAAGCCCCAAGTGGCCGTGCCATCCTGCCCCTCCACTCCC
GACTATGAGAACATGTTTGTGGGCCAGCCAGCAGCCGAGCACCAGTGGGATGAACAAGGG
GCTCACCCTTCAGAGGACAATGACTTTTACATCAACTACAAGGACATCGACCTGGCTTCC
CAGCCTGTCTACTGTAACCTGCAGTCACTGGGCCAGGCCTCAATGGATGAAGAGGAGTAC
GTGATCCCCGGGCACTGA

Clone variation with respect to NM_145256.2
880 c=>t
>OriGene 5' read for NM_145256 unedited
GGAATTTGTAAACGACTTACTATAGGGNNCGGCCGCGNNAATTCGGCACGAGGGAACGCC
AGCGACCCCAGCAGCGCTGCGGACGGTGCTGGCCGTGGCCGCTGCGGCCCCCGTGTCCAG
GTGGGCCAGGACGCAGCCTCTGGGCGCCGTCGCTTTTCCAGCATCGCAGAGGCAAAAGCG
TGGCAGTGGGACCCAAAAGGTTGCTTGAATGGGGGGCACCCTGGCATGGACGCTGCTGTT
GCCGCTGCTGCTGCGGGAGTCAGACAGCCTAGAACCGTCGTGCACCGTGTCCTCCGCGGA
TGTGGACTGGAACGCGGAGTTCAGTGCCACGTGCCTGAATTTCAGTGGCCTCAGCCTGAG
CCTGCCTCACAACCAGTCTCTGCGGGCCAGCAACGTGATTCTCCTTGACCTGTCTGGGAA
CGGCCTGCGAGAGCTTCCAGTGACCTTCTTTGCCCACCTGCAGAAGCTTGAGGTCCTGAA
CGTGCTACGCAACCCCTTGTCTCGTGTGGATGGGGCGCTGGCCGCCCGCTGTGACCTTGA
CCTGCAGGCCGACTGCAACTGTGCCCTGGAGTCCTGGCACGACATCCGCCGAGACAACTG
CTCTGGCCAGAAGCCTCTGCTCTGCTGGGACACAACCAGCTCCCAGCACAACCTCTCTGC
CTTCCTGGAGGTCAGCTGCGCCCCTGGCCTGGCCTCTGCAACTATCGGGGCAGTGGTGGT
CAGCGGGTGCCTGCTTCTTGGACTTGCCATCGCTGGCCCTGTGCTGGCCTGGAGACTCTG
GCGATGCCGAGTGGCCAGAAGCCGGGAGCTGAACANACCCTGGGCTGCTCANGATGGGCC
CAAAGCCCGGTTTAAGCTTGCAGCCACGGTACGGCAGCCGGAGCGCCCNCAGCCCCAGTG
GCCGTGCCATCTGCCCTCCACTCCCGATATGAGAACATGTTGTGGCCANCAGCAGCGAGC
ACAGTGGATGAACAGGGCTCACCTTCAGAGACA
Restriction Sites NotI-NotI     
ACCN NM_145256
Insert Size 1500 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_145256.1, NP_660299.1
RefSeq Size 1963 bp
RefSeq ORF 303 bp
Locus ID 126364
UniProt ID Q8N386
Domains LRR
Protein Families Transmembrane
Gene Summary Plays a role in the inhibition of RLR-mediated type I interferon signaling pathway by targeting DDX58/RIG-I for autophagic degradation. Interacts specifically with ISG15-associated DDX58 to promote interaction between DDX58 and the autophagic cargo receptor p62/SQSTM1 to mediate DDX58 degradation via selective autophagy (PubMed:29288164). Plays also a role in the inhibition of NF-kappa-B signaling pathway and inflammatory response by promoting the degradation of p65/RELA.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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