TIP30 (HTATIP2) (AF092095) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	CC3; SDR44U1; TIP30
Vector	pCMV6-XL4
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for AF092095, the custom clone sequence may differ by one or more nucleotides ATGGCCGAAACAGAAGCCCTGTCGAAGCTTCGGGAAGACTTCAGGATGCAGAATAAATCCGTCTTTATTT TGGGCGCCAGCGGAGAAACCGGCAGAGTGCTCTTAAAGGAAATCCTGGAGCAGGGCCTGTTTTCCAAAGT CACGCTCATTGGGCGGAGGAAGCTCACCTTCGACGAGGAAGCTTATAAAAATGTGAATCAAGAAGTGGTG GACTTTGAAAAGTTGGATGACTACGCCTCTGCCTTTCAAGGTCATGATGTTGGATTCTGTTGCCTGGGTA CCACCAGAGGGAAAGCTGGGGCGGTAAGGAAGGCATATGCTCTTTTCCCTTTTTGCTGGCCAGTAATATC AAGGATTCTTTTCTTGCTCACTCTTTTTCTTTGTGCCTGTTGCAATGCTTAA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for AF092095 unedited TGGATTTTGTATACGACTTACTATAGGGCGGCCGCGCAATTCGCACGAGGTGGGATGCTC TGATGGCCGGGCCTGCGGCGCTGAGCGCGGCGGCGGCGGCTGCTCTGGCGGCCGCCCTGC TCCTGCTGCGTCGTGAGGACCCGGGGCCGGGGGCTGGCCCATGGTAACCCCTCCGCGTAT GGGACCGAGCAGGGCCAGGTCTCCTGGCCGGGCCGGGGATACCGTGGGGTATGCCCAGTG ATGCCAGCAGCTTGTGGCACCTGGGCGCACCCTCCAGCTCGGGCCCCTTCCGATGGGTCT GCTGGCTCAGGTGCGGGCGATGGCCGGGGAGCCGCGCCCCGCACGTGACTCAGCACTTTC CCCAGAGCCCGGACTGCGGAGAACAATATCCTCCTCCCTAACAGATAAACAGCCCTTGTT CCTCGGGATAAGGACTGGCAGTCCCCTGACACCCTAAGACCGGCATCTGTCGATGTTATT TCCCCAGCATGGCCGAAACAGAAGCCCTGTCGAAGCTTCGGGAAGACTTCAGGATGCAGA ATAAATCCGTCTTTATTTTGGGCGCCAGCGGAGAAACCGGCAGAGTGCTCTTAAAGGAAA TCCTGGAGCAGGGCCTGTTTTCCAAAGTCACGCTCATTGGCCGGAGGAAGCTCACCTTCG ACGAGGAAGCTTATAAAAATGTGAATCAAGAAGTGGTGGACTTTGAAAAGTTGGATGACT ACGCCTCTGCCTTTCAGGTCATGATGTTGGATTCTGTTGCCTGGGTACCACCAGAGGGAA AGCTGGNGCGGANGGATTTGTTCGTGTTGACCGAGATTATGTGCTNGAGTCTGCAGAGCT GGGCAAAAGCTGGAGGTGCANACATTTCNACTTGCTATCCCTCTAAGGAGCTGATAAAAT CAAGCATTTTTTATATCTACCAGTTTANGGGAGAAGTAGAAGCCCAGGTTNGAGAATTNA AATTTNGATCGNTACTCTGNATTTAGGCCCTGG
Restriction Sites	NotI-NotI
ACCN	AF092095
Insert Size	1750 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	AF092095.1, AAC78331.1
RefSeq Size	784 bp
RefSeq ORF	402 bp
Locus ID	10553
Protein Families	Druggable Genome
Gene Summary	Oxidoreductase required for tumor suppression. NAPDH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect.[UniProtKB/Swiss-Prot Function]

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