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MC3R (NM_019888) Human Untagged Clone
CAT＃: SC113222
MC3R (untagged)-Human melanocortin 3 receptor (MC3R)
CNY 3,656.00
| Cited in 3 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BMIQ9; MC3; MC3-R; OB20; OQTL |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_019888, RT-PCR generated
ATGAGCATCCAAAAGAAGTATCTGGAGGGAGATTTTGTCTTTCCTGTGAGCAGCAGCAGC TTCCTACGGACCCTGCTGGAGCCCCAGCTCGGATCAGCCCTTCTGACAGCAATGAATGCT TCGTGCTGCCTGCCCTCTGTTCAGCCAACACTGCCTAATGGCTCGGAGCACCTCCAAGCC CCTTTCTTCAGCAACCAGAGCAGCAGCGCCTTCTGTGAGCAGGTCTTCATCAAGCCCGAG GTTTTCCTGTCTCTGGGCATCGTCAGTCTGCTGGAAAACATCCTGGTTATCCTGGCCGTG GTCAGGAACGGCAACCTGCACTCCCCGATGTACTTCTTTCTCTGCAGCCTGGCGGTGGCC GACATGCTGGTAAGTGTGTCCAATGCCCTGGAGACCATCATGATCGCCATCGTCCACAGC GACTACCTGACCTTCGAGGACCAGTTTATCCAGCACATGGACAACATCTTCGACTCCATG ATCTGCATCTCCCTGGTGGCCTCCATCTGCAACCTCCTGGCCATCGCCGTCGACAGGTAC GTCACCATCTTTTACGCGCTCCGCTACCACAGCATCATGACCGTGAGGAAGGCCCTCACC TTGATCGTGGCCATCTGGGTCTGCTGCGGCGTCTGTGGCGTGGTGTTCATCGTCTACTCG GAGAGCAAAATGGTCATTGTGTGCCTCATCACCATGTTCTTCGCCATGATGCTCCTCATG GGCACCCTCTACGTGCACATGTTCCTCTTTGCGCGGCTGCACGTCAAGCGCATAGCAGCA CTGCCACCTGCCGACGGGGTGGCCCCACAGCAACACTCATGCATGAAGGGGGCAGTCACC ATCACCATTCTCCTGGGCGTGTTCATCTTCTGCTGGGCCCCCTTCTTCCTCCACCTGGTC CTCATCATCACCTGCCCCACCAACCCCTACTGCATCTGCTACACTGCCCACTTCAACACC TACCTGGTCCTCATCATGTGCAACTCCGTCATCGACCCACTCATCTACGCTTTCCGGAGC CTGGAATTGCGCAACACCTTTAGGGAGATTCTCTGTGGCTGCAACGGCATGAACTTGGGA TAG >OriGene 5' read for NM_019888 unedited
TTTGGGGATTTTTGGATTTGTNAAACGACTTCACTATAGGCGGCCGCCAGTCGTGAGGAT ATCTGCAGAATTCGGCTTATGAGCATCCAAAAGAATATCTGGAGGGAGATTTTGTCTTTC CTGTGAGCAGCAGCAGCTTCCTACGGACCCTGCTGGAGCCCCAGCTCGGATCAGCCCTTC TGACAGCAATGAATGCTTCGTGCTGCCTGCCCTCTGTTCAGCCAACACTGCCTAATGGCT CGGAGCACCTCCAAGCCCCTTTCTTCAGCAACCAGAGCAGCAGCGCCTTCTGTGAGCAGG TCTTCATCAAGCCCGAGGTTTTCCTGTCTCTGGGCATCGTCAGTCTGCTGGAAAACATCC TGGTTATCCTGGCCGTGGTCAGGAACGGCAACCTGCACTCCCCGATGTACTTCTTTCTCT GCAGCCTGGCGGTGGCCGACATGCTGGTAAGTGTGTCCAATGCCCTGGAGACCATCATGA TCGCCATCGTCCACAGCGACTACCTGACCTTCGAGGACCAGTTTATCCAGCACATGGACA ACATCTTCGACTCCATGATCTGCATCTCCCTGGTGGCCTCCATCTGCAACCTCCTGGCCA TCGCCGTCGACAGGTACGTCACCATCTTTTACGCGCTCCGCTACCACAGCATCATGACCG TGAGGAAGGCCCTCACCTTGATCGTGGCCATCTGGGTCTGCTGCGGCGTCTGTGGCGTGG TGTTCATCGTCTACTCGGAGAGCANAAGGTCATTGTGTGCCTCATCACCATGTTCTTCGC CATGATGCTNCTCATGGGCACCCTCTACGTGCACATGTTCCTCTTTGCGCGGCTGCACGT CAAGCGCATAGCAGCACTGCCATCTGCCGACCGGGGTGGCCCCACAGCAACACTCT >OriGene 3' read for NM_019888 unedited
TCTANATNCGACAAGACTTGATATCGGTACCGAGCTCGGATCCACTAGTAACGGCCGCCA GTGTGCTGGAATTCGGCTTCTATCCCAAGTTCATGCCGTTGCAGCCACAGAGAATCTCCC TAAAGGTGTTGCGCAATTCCAGGCTCCGGAAAGCGTAGATGAGTGGGTCGATGACGGAGT TGCACATGATGAGGACCAGGTAGGTGTTGAAGTGGGCAGTGTAGCAGATGCAGTAGGGGT TGGTGGGGCAGGTGATGATGAGGACCAGGTGGAGGAAGAAGGGGGCCCAGCAGAAGATGA ACACGCCCAGGAGAATGGTGATGGTGACTGCCCCCTTCATGCATGAGTGTTGCTGTGGGG CCACCCCGTCGGCAGGTGGCAGTGCTGCTATGCGCTTGACGTGCAGCCGCGCAAAGAGGA ACATGTGCACGTAGAGGGTGCCCATGAGGAGCATCATGGCGAAGAACATGGTGATGAGGC ACACAATGACCATTTTGCTCTCCGAGTAGACGATGAACACCACGCCACAGACGCCGCAGC AGACCCAGATGGCCACGATCAAGGTGAGGGCCTTCCTCACGGTCATGATGCTGTGGTAGC GGAGCGCGTAAAAGATGGTGACGTACCTGTCGACGGCGATGGCCAGGATGTTGCAGATGG AGGCCACCAGGGAGATGCAGATCATGGAGTCGAAGATGTTGTCCATGTGCTGGATAAACT GGTCCTCGAAGGTCAGGTAGTCGCTGTGGACGATGGGCGATCATGATGGTCTCANGGCAT TGGACACACTTACCAGCATGTCGGCCACCGCCAGGCTGCAGAGAAAGGAGTACATCGGGG GATTGCATGTTGCCC |
| Restriction Sites | Please inquire |
| ACCN | NM_019888 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_019888.2, NP_063941.2 |
| RefSeq Size | 1083 bp |
| RefSeq ORF | 1083 bp |
| Locus ID | 4159 |
| UniProt ID | P41968 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Neuroactive ligand-receptor interaction |
| Gene Summary | This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans. [provided by RefSeq, Jul 2008] |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
A proopiomelanocortin-derived peptide sequence enhances plasma stability of peptide drugs.
,null,
FEBS letters
,PubMed ID 32506501
[MC3R]
|
|
Molecular evolution of the proopiomelanocortin system in Barn owl species
,Löw, K;Ducrest, AL;San-Jose, LM;Simon, C;Uva, V;Seidah, NG;Pasquato, A;Kunz, S;Roulin, A;,
PLoS ONE
,PubMed ID 32369484
[MC3R]
|
|
Biased Agonism as a Novel Strategy To Harness the Proresolving Properties of Melanocortin Receptors without Eliciting Melanogenic Effects
,Montero-Melendez, T;Gobbetti, T;Cooray, SN;Jonassen, TE;Perretti, M;,
J. Immunol.
,PubMed ID 25725103
[MC3R]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC215195 | MC3R (Myc-DDK-tagged)-Human melanocortin 3 receptor (MC3R) |
CNY 3,656.00 |
|
| RC215195L1 | Lenti ORF clone of Human melanocortin 3 receptor (MC3R), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC215195L2 | Lenti ORF clone of Human melanocortin 3 receptor (MC3R), mGFP tagged |
CNY 5,890.00 |
|
| RC215195L3 | Lenti ORF clone of Human melanocortin 3 receptor (MC3R), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC215195L4 | Lenti ORF clone of Human melanocortin 3 receptor (MC3R), mGFP tagged |
CNY 5,890.00 |
|
| RG215195 | MC3R (tGFP-tagged) - Human melanocortin 3 receptor (MC3R) |
CNY 5,256.00 |
