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Calpain 6 (CAPN6) (NM_014289) Human Untagged Clone
CAT＃: SC115094
CAPN6 (untagged)-Human calpain 6 (CAPN6)
CNY 4,784.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CalpM; CANPX; CAPNX; DJ914P14.1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC115094 sequence for NM_014289 edited (data generated by NextGen Sequencing)
ATGGGTCCTCCTCTGAAGCTCTTCAAAAACCAGAAATACCAGGAACTGAAGCAGGAATGC ATCAAAGACAGCAGACTTTTCTGTGATCCAACATTTCTGCCTGAGAATGATTCTCTTTTC TACAACCGACTGCTTCCTGGAAAGGTGGTGTGGAAACGTCCCCAGGACATCTGTGATGAC CCCCATCTGATTGTGGGCAACATTAGCAACCACCAGCTGACCCAAGGGAGACTGGGGCAC AAGCCAATGGTTTCTGCATTTTCCTGTTTGGCTGTTCAGGAGTCTCATTGGACAAAGACA ATTCCCAACCATAAGGAACAGGAATGGGACCCTCAAAAAACAGAAAAATACGCTGGGATA TTTCACTTTCGTTTCTGGCATTTTGGAGAATGGACTGAAGTGGTGATTGATGACTTGTTG CCCACCATTAACGGAGATCTGGTCTTCTCTTTCTCCACTTCCATGAATGAGTTTTGGAAT GCTCTGCTGGAAAAAGCTTATGCAAAGCTGCTAGGCTGTTATGAGGCCCTGGATGGTTTG ACCATCACTGATATTATTGTGGACTTCACGGGCACATTGGCTGAAACTGTTGACATGCAG AAAGGAAGATACACTGAGCTTGTTGAGGAGAAGTACAAGCTATTCGGAGAACTGTACAAA ACATTTACCAAAGGTGGTCTGATCTGCTGTTCCATTGAGTCTCCCAATCAGGAGGAGCAA GAAGTTGAAACTGATTGGGGTCTGCTGAAGGGCCATACCTATACCATGACTGATATTCGC AAAATTCGTCTTGGAGAGAGACTTGTGGAAGTCTTCAGTGCTGAGAAGGTGTATATGGTT CGCCTGAGAAACCCCTTGGGAAGACAGGAATGGAGTGGCCCCTGGAGTGAAATTTCTGAA GAGTGGCAGCAACTGACTGCATCAGATCGCAAGAACCTGGGGCTTGTTATGTCTGATGAT GGAGAGTTTTGGATGAGCTTGGAGGACTTTTGCCGCAACTTTCACAAACTGAATGTCTGC CGCAACGTGAACAACCCTATTTTTGGCCGAAAGGAGCTGGAATCGGTGTTGGGATGCTGG ACTGTGGATGATGATCCCCTGATGAACCGCTCAGGAGGCTGCTATAACAACCGTGATACC TTCCTGCAGAATCCCCAGTACATCTTCACTGTGCCTGAGGATGGGCACAAGGTCATTATG TCACTGCAGCAGAAGGACCTGCGCACTTACCGCCGAATGGGAAGACCTGACAATTACATC ATTGGCTTTGAGCTCTTCAAGGTGGAGATGAACCGCAAATTCCGCCTCCACCACCTCTAC ATCCAGGAGCGTGCTGGGACTTCCACCTATATTGACACCCGCACAGTGTTTCTGAGCAAG TACCTGAAGAAGGGCAACTATGTGCTTGTCCCAACCATGTTCCAGCATGGTCGCACCAGC GAGTTTCTCCTGAGAATCTTCTCTGAAGTGCCTGTCCAGCTCAGGGAACTGACTCTGGAC ATGCCCAAAATGTCCTGCTGGAACCTGGCTCGTGGCTACCCGAAAGTAGTTACTCAGATC ACTGTTCACAGTGCTGAGGACCTGGAGAAGAAGTATGCCAATGAAACTGTAAACCCATAT TTGGTCATCAAATGTGGAAAGGAGGAAGTCCGTTCTCCTGTCCAGAAGAATACAGTTCAT GCCATTTTTGACACCCAGGCCATTTTCTACAGAAGGACCACTGACATTCCTATTATAGTA CAGGTCTGGAACAGCCGAAAATTCTGTGATCAGTTCTTGGGGCAGGTTACTCTGGATGCT GACCCCAGCGACTGCCGTGATCTGAAGTCTCTGTACCTGCGTAAGAAGGGTGGTCCAACT GCCAAAGTCAAGCAAGGCCACATCAGCTTCAAGGTTATTTCCAGCGATGATCTCACTGAG CTCTAA Clone variation with respect to NM_014289.3 1026 t=>c >OriGene 5' read for NM_014289 unedited
ATTGGGATTTGTAATCCGACTTTACTATAGGGCGGACCGACGCATTCGGCACGAGGGCTA ACAGCAGCAGCGGCAACGGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGGGCTC CTGGGATAACTCAGGCATAGTTCAACACTATGGGTCCTCCTCTGAAGCTCTTCAAAAACC AGAAATACCAGGAACTGAAGCAGGAATGCATCAAAGACAGCAGACTTTTCTGTGATCCAA CATTTCTGCCTGAGAATGATTCTCTTTTCTACAACCGACTGCTTCCTGGAAAGGTGGTGT GGAAACGTCCCCAGGACATCTGTGATGACCCCCATCTGATTGTGGGCAACATTAGCAACC ACCAGCTGACCCAAGGGAGACTGGGGCACAAGCCAATGGTTTCTGCATTTTCCTGTTTGG CTGTTCAGGAGTCTCATTGGACAAAGACAATTCCCAACCATAAGGAACAGGAATGGGACC CTCAAAAAACAGAAAAATACGCTGGGATATTTCACTTTCGTTTCTGGCATTTTGGAGAAT GGACTGAAGTGGTGATTGATGACTTGTTGCCCACCATTAACGGAGATCTGGTCTTCTCTT TCTCCACTTCCATGAATGAGTTTTGGAATGCTCTGCTGNGAAAAGCTTATGCAAAGCTGC TAGGCTGTTATGAGGCCCTGGATGGTTTGACCATCACTGATATTATTGTGGACTTCACGG GCACATTGGCTGANACTGNTGACATGCAGAAAGGAGATACACTGAGCTTGTTGAGGAGAA AGTACAGCTATTTCGAGAACTGTACANACATTTACCCAAGGTGGTCTGATCTGCNTGTCC ATTGAGTCTCCAATCAGGGAGGAGCAGAAGTGAAACTGATGGGGGTCTGCTGAAGGCCAT ACCTATCCATGACTGATATCGCAAA >OriGene 3' read for NM_014289 unedited
GGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTACTGAATATGAACTTTATTGT GATTTGGTTTATGTAAGGCAGTGTAGTGAAGGCACTGCAGAAGTTAAACAGACTGGAAAA CATGGTAAAAAATGAGCGAGCTAAAAATGAATGCTTGCTGGTCTAGGTAGGCTAAGTACT ACAACTATGTTTCTTTTTCATCATTGCAGAAGCGTTGAAATATTGTTGAAGGTGGGGGTT TGGGGTGGAATTAGGGAAGGCTTCATGGAGGAGGTGGCATTTATACTGGGCCTTGAAGGA GGGGCAGAAAGTTGATAGGTTAAGATGGAGGGAAGTACATTTCATAATGACTGACTCTAG AGAAAATTCTGTAGAAGTACTGAAAAATGAGAGGGCAAACAAACACCCCCAGCGAGTGAA GCATCCCAACTGAGAGAAAAGTCTGAGGAGTCTGGGCTGGGACCAAAGTCTCAAGTCCCC AGATGGGGTCTTCAGTACAAATGATATTAGGAGGCACAGGACAATGGGCTTGTTTGTAAA CCTAGCAGCAGCGAGAGGTTTCACATTGCAGTCAGGGGCCCCAAACTGGCTGTAATATGT CTGGATGAATTCTCTCATCTTTTAGGTGTGTATGGGACTTACTTATCTTTCCTCTTGCCC ACTGACTGCCTGAATGGTAGTTCGTGCGCGCCCATGTGCGCGTGTGTGAATGTANGTGTG TGTGGATGGGTGGGGGACCCANGCTTTGTCTCCCACTGCAGCTTCTTCCACTTTTCCGTC TTGTGGCACACAGAAGGCTTCCATTGAGCTGAAGCTAGGCCCCTCTCACTGGTCTAGACT TCATTGAATTCACCTCTTGCATAAGCCCCAGGAAGCTCTCTCACATGAAGGGTAAAATTA CTGTCGGGGGCGACTTGTGTAAGGGCAGACTACCCTTCCCGAGTGATAAGGCGCTAAGGT GGGCGCCCCTCCCACACCACAT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_014289 |
| Insert Size | 3630 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_014289.2, NP_055104.2 |
| RefSeq Size | 3568 bp |
| RefSeq ORF | 1926 bp |
| Locus ID | 827 |
| UniProt ID | Q9Y6Q1 |
| Domains | C2, Calpain_III |
| Protein Families | Druggable Genome, Protease |
| Gene Summary | Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis. [provided by RefSeq, Nov 2009] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200539 | CAPN6 (Myc-DDK-tagged)-Human calpain 6 (CAPN6) |
CNY 4,776.00 |
|
| RC200539L1 | Lenti ORF clone of Human calpain 6 (CAPN6), Myc-DDK-tagged |
CNY 7,176.00 |
|
| RC200539L2 | Lenti ORF clone of Human calpain 6 (CAPN6), mGFP tagged |
CNY 5,890.00 |
|
| RC200539L3 | Lenti ORF clone of Human calpain 6 (CAPN6), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC200539L4 | Lenti ORF clone of Human calpain 6 (CAPN6), mGFP tagged |
CNY 5,890.00 |
|
| RG200539 | CAPN6 (tGFP-tagged) - Human calpain 6 (CAPN6) |
CNY 6,376.00 |
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