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SOS1 (NM_005633) Human Untagged Clone
CAT＃: SC116602
SOS1 (untagged)-Human son of sevenless homolog 1 (Drosophila) (SOS1)
CNY 13,688.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GF1; GGF1; GINGF; HGF; NS4; SOS-1 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_005633, the custom clone sequence may differ by one or more nucleotides
ATGCAGGCGCAGCAGCTGCCCTACGAGTTTTTCAGCGAAGAGAACGCGCCCAAGTGGCGGGGACTACTGG TGCCTGCGCTGAAAAAGGTCCAGGGGCAAGTTCATCCTACTCTCGAGTCTAATGATGATGCTCTTCAGTA TGTTGAAGAATTAATTTTGCAATTATTAAATATGCTATGCCAAGCTCAGCCCCGAAGTGCTTCAGATGTA GAGGAACGTGTTCAAAAAAGTTTCCCTCATCCAATTGATAAATGGGCAATAGCTGATGCCCAATCAGCTA TTGAAAAGAGGAAGCGAAGAAACCCTTTATCTCTCCCAGTAGAAAAAATTCATCCTTTATTAAAGGAGGT CCTAGGTTATAAAATTGACCACCAGGTTTCTGTTTACATAGTAGCAGTCTTAGAATACATTTCTGCAGAC ATTTTAAAGCTGGTTGGGAATTATGTAAGAAATATACGGCATTATGAAATTACAAAACAAGATATTAAAG TGGCAATGTGTGCTGACAAGGTATTGATGGATATGTTTCATCAAGATGTAGAAGATATTAATATATTATC TTTAACTGACGAAGAGCCTTCCACCTCAGGAGAACAAACTTACTATGATTTGGTAAAAGCATTTATGGCA GAAATTCGACAATATATAAGGGAACTAAATCTAATTATAAAAGTTTTTAGAGAGCCCTTTGTCTCCAATT CAAAATTGTTTTCAGCTAATGATGTAGAAAATATATTTAGTCGCATAGTAGATATACATGAACTTAGTGT AAAGTTACTGGGCCATATAGAAGATACAGTAGAAATGACAGATGAAGGCAGTCCCCATCCACTAGTAGGA AGCTGCTTTGAAGACTTAGCAGAGGAACTGGCATTTGATCCATATGAATCGTATGCTCGAGATATTTTGC GACCTGGTTTTCATGATCGTTTCCTTAGTCAGTTATCAAAGCCTGGGGCAGCACTTTATTTGCAGTCAAT AGGCGAAGGTTTCAAAGAAGCTGTTCAATATGTTTTACCCAGGCTGCTTCTGGCCCCTGTTTACCACTGT CTCCATTACTTTGAACTTTTGAAGCAGTTAGAAGAAAAAAGTGAAGATCAAGAAGACAAGGAATGTTTAA AACAAGCAATAACAGCTTTGCTTAATGTTCAGAGTGGTATGGAAAAAATATGTTCTAAAAGTCTTGCAAA ACGAAGACTGAGTGAATCTGCATGTCGGTTTTATAGTCAGCAAATGAAGGGGAAACAACTAGCAATCAAG AAGATGAACGAGATTCAGAAGAATATTGATGGTTGGGAGGGAAAAGACATTGGACAGTGTTGTAATGAAT TTATAATGGAAGGAACTCTTACACGTGTAGGAGCCAAACATGAGAGACACATATTTCTCTTTGATGGCTT AATGATTTGCTGTAAATCAAATCATGGGCAGCCAAGACTTCCTGGTGCTAGCAATGCAGAATATCGTCTT AAAGAAAAGTTTTTTATGCGAAAGGTACAAATTAATGATAAAGATGACACCAATGAATACAAGCATGCTT TTGAAATAATTTTAAAAGATGAAAATAGTGTTATATTTTCTGCCAAGTCAGCTGAAGAGAAAAACAATTG GATGGCAGCATTGATATCTTTACAGTACCGGAGTACACTGGAAAGGATGCTTGATGTAACAATGCTACAG GAAGAGAAAGAGGAGCAGATGAGGCTGCCTAGTGCTGATGTTTATAGATTTGCAGAGCCTGACTCTGAAG AGAATATTATATTTGAAGAGAACATGCAGCCCAAGGCTGGAATTCCAATTATCAAAGCAGGAACTGTTAT TAAACTTATAGAGAGGCTTACGTACCATATGTACGCAGATCCCAATTTTGTTCGGACATTTCTTACAACA TACAGATCCTTTTGCAAACCTCAAGAACTACTGAGTCTTATAATAGAAAGGTTTGAAATTCCAGAGCCTG AGCCAACAGAAGCTGATCGCATAGCTATAGAGAATGGAGATCAACCCTTGAGTGCAGAACTGAAAAGATT TAGAAAAGAATATATACAGCCTGTGCAACTGCGAGTATTAAATGTATGTCGGCACTGGGTAGAGCACCAC TTCTATGATTTTGAAAGAGATGCATATCTTTTGCAACGAATGGAAGAATTTATTGGAACAGTAAGAGGTA AAGCAATGAAAAAATGGGTTGAATCCATCACTAAAATAATCCAAAGGAAAAAAATTGCAAGAGACAATGG ACCAGGTCATAATATTACATTTCAGAGTTCACCTCCCACAGTTGAGTGGCATATAAGCAGACCTGGGCAC ATAGAGACTTTTGACCTGCTCACCTTACACCCAATAGAAATTGCTCGACAACTCACTTTACTTGAATCAG ATCTATACCGAGCTGTACAGCCATCAGAATTAGTTGGAAGTGTGTGGACAAAAGAAGACAAAGAAATTAA CTCTCCTAATCTTCTGAAAATGATTCGACATACCACCAACCTCACTCTGTGGTTTGAGAAATGTATTGTA GAAACTGAAAATTTAGAAGAAAGAGTAGCTGTGGTGAGTCGAATTATTGAGATTCTACAAGTCTTTCAAG AGTTGAACAACTTTAATGGTGTCCTTGAGGTTGTCAGTGCTATGAATTCATCACCTGTTTACAGACTAGA CCACACATTTGAGCAAATACCAAGTCGCCAGAAGAAAATTTTAGAAGAAGCTCATGAATTGAGTGAAGAT CACTATAAGAAATATTTGGCAAAACTCAGGTCTATTAATCCACCATGTGTGCCTTTCTTTGGAATTTATC TCACTAATATCTTGAAAACAGAAGAAGGCAACCCTGAGGTCCTAAAAAGACATGGAAAAGAGCTTATAAA CTTTAGCAAAAGGAGGAAAGTAGCAGAAATAACAGGAGAGATCCAGCAGTACCAAAATCAGCCTTACTGT TTACGAGTAGAATCAGATATCAAAAGGTTCTTTGAAAACTTGAATCCGATGGGAAATAGCATGGAGAAGG AATTTACAGATTATCTTTTCAACAAATCCCTAGAAATAGAACCACGAAACCCTAAGCCTCTCCCAAGATT TCCAAAAAAATATAGCTATCCCCTAAAATCTCCTGGTGTTCGTCCATCAAACCCAAGACCAGGTACCATG AGGCATCCCACACCTCTGCAGCAGGAGCCAAGGAAAATTAGTTATAGTAGGATCCCTGAAAGTGAAACAG AAAGTACAGCATCTGCACCAAATTCTCCAAGAACACCGTTAACACCTCCGCCTGCTTCTGGTGCTTCCAG TACCACAGATGTTTGCAGTGTATTTGATTCCGATCATTCGAGCCCTTTTCACTCAAGCAATGATACCGTC TTTATCCAAGTTACTCTGCCCCATGGCCCAAGATCTGCTTCTGTATCATCTATAAGTTTAACCAAAGGCA CTGATGAAGTGCCTGTCCCTCCTCCTGTTCCTCCACGAAGACGACCAGAATCTGCCCCAGCAGAATCTTC ACCATCTAAGATTATGTCTAAGCATTTGGACAGTCCCCCAGCCATTCCTCCTAGGCAACCCACATCAAAA GCCTATTCACCACGATATTCAATATCAGACCGGACCTCTATCTCAGACCCTCCTGAAAGCCCTCCCTTAT TACCACCACGAGAACCTGTGAGGACACCTGATGTTTTCTCAAGCTCACCACTACATCTCCAACCTCCCCC TTTGGGCAAAAAAAGTGACCATGGCAATGCCTTCTTCCCAAACAGCCCTTCCCCCTTTACACCACCTCCT CCTCAAACACCTTCTCCTCACGGCACAAGAAGGCATCTGCCATCACCACCATTGACACAAGAAGTGGACC TTCATTCCATTGCTGGGCCGCCTGTTCCTCCACGACAAAGCACTTCTCAACATATCCCTAAACTCCCTCC AAAAACTTACAAAAGGGAGCACACACACCCATCCATGCACAGAGATGGACCACCACTGTTGGAGAATGCC CATTCTTCCTGA >OriGene 5' read for NM_005633 unedited
CTATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCGCCCANAG GCGCCCCGGGGGCACCATGCAGGCGCAGCAGCTGCCCTACGAGTTTTTCAGCGAAGAGAA CGCGCCCAAGTGGCGGGGACTACTGGTGCCTGCGCTGAAAAAGGTCCAGGGGCAAGTTCA TCCTACTCTCGAGTCTAATGATGATGCTCTTCAGTATGTTGAAGAATTAATTTTGCAATT ATTAAATATGCTATGCCAAGCTCAGCCCCGAAGTGCTTCAGATGTAGAGGAACGTGTTCA AAAAAGTTTCCCTCATCCAATTGATAAATGGGCAATAGCTGATGCCCAATCAGCTATTGA AAAGAGGAAGCGAAGAAACCCTTTATCTCTCCCAGTAGAAAAAATTCATCCTTTATTAAA GGAGGTCCTAGGTTATAAAATTGACCACCAGGTTTCTGTTTACATAGTAGCAGTCTTAGA ATACATTTCTGCAGACATTTTAAAGCTGGTTGGGAATTATGTAAGAAATATACGGCATTA TGAAATTACAAAACAAGATATTAAAGTGGCAATGTGTGCTGACAAGGTATTGATGGATAT GTTTCATCAAGATGTAGAAGATATTAATATATTATCTTTAACTGACGAAGAGCCTTCCAC CTCAGGAGAACAAACTTACTATGATTTGGTAAAAGCATTTATGGCAGAAATTCGACAATA TATAAGGGAACTAAATCTAATTATAAAAGTTTTTAGAGAGCCCTTTGTCTCCAATTCAAA ATTGTTTTCAGCTAATGATGTAGAAAATATATTTAGTCGCATAGTAGATATACATGAACT TTAGTGTAAGTTACTGNGCCATATAGAGATACAGTNGAAATGACAGATGAAGGCAGTNCC CATNCACTAGTANGAAGCTGNCTTGAAGACTTAGCAGAGGAACTGGCATTTGATCCATAT GATCGTATGCTCGAAAATTTTGCGACCTGGTTNCATGATCGNTNCCTAGTCAAN >OriGene 3' read for NM_005633 unedited
GGACACTGGGGGNNAGGGGTCACAGGGNATGCCACCCGGGCTCTGTTCAGGAAACAGCTA TGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAAGTATTTGTATCTT TATTCAATTAAATTAAAACAGACCTGCCAGGTATATTATATAACATTCACTATATACATA TGATTTAGGCAATGCAAGATAATTCTAGATATGCTGATTACTCAACTATGTGTAAAACAT GAGCGGTGTCAGTGATGCCCAGCAGGTGCTCCTTTTCACATTGGGTGCCTGCATTAGCNT GGTGTGGTTAGAGGGATAGCTACGAGCCATGACNTGGAAGACCNNTNAACTTCTGTGGGN NAANGNGGGAAGGTGACGGTCTNGCCTAGGTGACCGGTCTCCGGGGTGCGCCCTGGGTAG GTGGCGGCTGTCCTTTCTTTGGCCCCTCTTCTGGCGGCTTCGGGGGGCGGGGGTTCCCTT TTGGGGGGGCCGCGCCGGGGGGTTTTCGTCTTCCCCTTCTGCGCCCCCTCGGGCTCGGCC GGCGCCCCCGCGCCCCCGGGGGCGGGAGGTCCTTCCCCGCCGGCTCGCCGCGCTGTCCCG GGGGCCGCGCGCGGCGGCTTCTCCGGCCGTCCCTTCCTCTCTCTTCCGCGCCCCCGAACG CGGACCCGGGCGGCGCTCCCGCGCCCGAGACCGGCGCTGGGCCGCGGGGCAACAGGCTTG GCGCGCGGCCGTCGCGGGGGCGGTCGCGCGTGCCCCTACACGGCCGCTCGGGCCGCCCGC GCNGCAGGGAGCCACCGGCGGTGGTGGTCCGCTTCTGTTGGGCCGGGCCGGGCGCACCGC ACGCTTCCCCGCCACACAGACAGAACCAAGAAAAAAGAAAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_005633 |
| Insert Size | 4700 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005633.2, NP_005624.2 |
| RefSeq Size | 4002 bp |
| RefSeq ORF | 4002 bp |
| Locus ID | 6654 |
| UniProt ID | Q07889 |
| Domains | RhoGEF, RasGEFN, PH, RasGEF |
| Protein Families | Druggable Genome |
| Protein Pathways | Acute myeloid leukemia, B cell receptor signaling pathway, Chemokine signaling pathway, Chronic myeloid leukemia, Colorectal cancer, Dorso-ventral axis formation, Endometrial cancer, ErbB signaling pathway, Fc epsilon RI signaling pathway, Focal adhesion, Gap junction, Glioma, GnRH signaling pathway, Insulin signaling pathway, Jak-STAT signaling pathway, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Non-small cell lung cancer, Pathways in cancer, Prostate cancer, Regulation of actin cytoskeleton, Renal cell carcinoma, T cell receptor signaling pathway |
| Gene Summary | This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq, Jul 2008] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC213531 | SOS1 (Myc-DDK-tagged)-Human son of sevenless homolog 1 (Drosophila) (SOS1) |
CNY 13,920.00 |
|
| RC213531L1 | Lenti ORF clone of Human son of sevenless homolog 1 (Drosophila) (SOS1), Myc-DDK-tagged |
CNY 16,320.00 |
|
| RC213531L2 | Lenti ORF clone of Human son of sevenless homolog 1 (Drosophila) (SOS1), mGFP tagged |
CNY 12,730.00 |
|
| RC213531L3 | Lenti ORF clone of Human son of sevenless homolog 1 (Drosophila) (SOS1), Myc-DDK-tagged |
CNY 12,730.00 |
|
| RC213531L4 | Lenti ORF clone of Human son of sevenless homolog 1 (Drosophila) (SOS1), mGFP tagged |
CNY 12,730.00 |
|
| RG213531 | SOS1 (tGFP-tagged) - Human son of sevenless homolog 1 (Drosophila) (SOS1) |
CNY 15,520.00 |
