GRPR (NM_005314) Human Untagged Clone
CAT#: SC116819
GRPR (untagged)-Human gastrin-releasing peptide receptor (GRPR)
CNY 3,656.00
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | BB2; BB2R; BRS2 |
Vector | pCMV6-XL4 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF within SC116819 sequence for NM_005314 edited (data generated by NextGen Sequencing)
ATGGCTCTAAATGACTGTTTCCTTCTGAACTTGGAGGTGGACCATTTCATGCACTGCAAC ATCTCCAGTCACAGTGCGGATCTCCCCGTGAACGATGACTGGTCCCACCCGGGGATCCTC TATGTCATCCCTGCAGTTTATGGGGTTATCATTCTGATAGGCCTCATTGGCAACATCACT TTGATCAAGATCTTCTGTACAGTCAAGTCCATGCGAAACGTTCCAAACCTGTTCATTTCC AGTCTGGCTTTGGGAGACCTGCTCCTCCTAATAACGTGTGCTCCAGTGGATGCCAGCAGG TACCTGGCTGACAGATGGCTATTTGGCAGGATTGGCTGCAAACTGATCCCCTTTATACAG CTTACCTCTGTTGGGGTGTCTGTCTTCACACTCACGGCGCTCTCGGCAGACAGATACAAA GCCATTGTCCGGCCAATGGATATCCAGGCCTCTCATGCCCTGATGAAGATCTGCCTCAAA GCCGCCTTTATCTGGATCATCTCCATGCTGCTGGCCATTCCAGAGGCCGTGTTTTCTGAC CTCCATCCCTTCCATGAGGAAAGCACCAACCAGACCTTCATTAGCTGTGCCCCATACCCA CACTCTAATGAGCTTCACCCCAAAATCCATTCTATGGCTTCCTTTCTGGTCTTCTACGTC ATTCCACTGTCGATCATCTCTGTTTACTACTACTTCATTGCTAAAAATCTGATCCAGAGT GCTTACAATCTTCCCGTGGAAGGGAATATACATGTCAAGAAGCAGATTGAATCCCGGAAG CGACTTGCCAAGACAGTGCTGGTGTTTGTGGGCCTGTTCGCCTTCTGCTGGCTCCCCAAT CATGTCATCTACCTGTACCGCTCCTACCACTACTCTGAGGTGGACACCTCCATGCTCCAC TTTGTCACCAGCATCTGTGCCCGCCTCCTGGCCTTCACCAACTCCTGCGTGAACCCCTTT GCCCTCTACCTGCTGAGCAAGAGTTTCAGGAAACAGTTCAACACTCAGCTGCTCTGTTGC CAGCCTGGCCTGATCATCCGGTCTCACAGCACTGGAAGGAGTACAACCTGCATGACCTCC CTCAAGAGTACCAACCCCTCCGTGGCCACCTTTAGCCTCATCAATGGAAACATCTGTCAC GAGCGGTATGTCTAG Clone variation with respect to NM_005314.2 >OriGene 5' read for NM_005314 unedited
NGGTCAAAATTGTATACGACTCACTATAGGGCGGCCGCGATTCGCCCTTCTTATCTTCAT CTTCACTCGGTTGCAAAATCAATAGTTAAGAAATAGCATCTAAGGGAACTTTTAGGTGGN GAAAAAAAATCTAGAGATGGCTCTAAATGACTGTTTCCTTCTGAACTTGGAGGTGGACCA TTTCATGCACTGCAACATCTCCAGTCACAGTGCGGATCTCCCCGTGAACGATGACTGGTC CCACCCGGGGATCCTCTATGTCATCCCTGCAGTTTATGGGGTTATCATTCTGATAGGCCT CATTGGCAACATCACTTTGATCAAGATCTTCTGTACAGTCAAGTCCATGCGAAACGTTCC AAACCTGTTCATTTCCAGTCTGGCTTTGGGAGACCTGCTCCTCCTAATAACGTGTGCTCC AGTGGATGCCAGCAGGTACCTGGCTGACAGATGGCTATTTGGCAGGATTGGCTGCAAACT GATCCCCTTTATACAGCTTACCTCTGTTGGGGTGTCTGTCTTCACACTCACGGCGCTCTC GGCAGACAGATACAAAGCCATTGTCCGGCCAATGGATATCCAGGCCTCTCATGCCCTGAT GAAGATCTGCCTCAAAGCCGCCTTTATCTGGATCATCTCCATGCTGCTGGCCATTCCAGA GGCCGTGTTTTCTGACCTCCATCCCTTCCATGAGGAAAGCACCAACCAGACCTTCATTAG CTGTGCCCCATACCCACACTCTAATGAGCTTCACCCCAAAATCCATTCTATGGCTTCCTT TCTGGTCTTCTACGTCATTCCACTGTCGATCATCTCTGTTTACTACTACTTCATTGCTAA AAATCTGATCCAGAGTGCTTACCATCTTCCCGTGGAAGGAATATACATGTCAAGAAGCAG ATTGAATCCCNGAAGCGACTTGNNCAGACGTGCTGGTGTTTGTGG >OriGene 3' read for NM_005314 unedited
NNGGGCCATGGGGATGGCAACTTCCAGGGCCAGNAAAGCACTGGGGNAGGGTCACAGGGA TGCCACCCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGACAA GCTTGATATCGGTACCAGATCTGAATTCGCCCTTCACCTACACCACTCAGGAGCATTCTG AAGGCTCTTTGGAGGGCACAGACACAACAATGGATGCAAGGGTTCCTGTCTAGCCATAAA GCAAAACCGTCCCTCAGGGGGCAAAATCAAGGGTCAATCTAGACATACCGCTCGTGACAG ATGTTTCCATTGATGAGGCTAAAGGTGGCCACGGAGGGGTTGGTACTCTTGAGGGAGGTC ATGCAGGTTGTACTCCTTCCAGTGCTGTGAGACCGGATGATCAGGCCAGGCTGGCAACAG AGCAGCTGAGTGTTGAACTGTTTCCTGAAACTCTTGCTCAGCAGGTAGAGGGCAAAGGGG TTCACGCAGGAGTTGGTGAAGGCCAGGAGGCGGGCACAGATGCTGGTGACAAAGTGGAGN CATGGAGGTGTCCACCTCAGAGTAGTGGTAGGAGCGGTACAGGTAGATGACATGATTGGG GAGCCAGCAGAAGGCGAACAGGCCCACAAACACCAGCACTGTCTTGGCAAGTCGCTTCCG GGATTCAATCTGCTTCTTGACATGTATATTCCCTTCCCGGGAAGATTGTAGCACTCTGGA TCAGATTTTTAGCAATGAAGTAGTAGTAAACAGAGATGATCGACAGTGAATGACGTAGAA GACCAGAAAGGAGCATAGATGGNATTTGGGGGTAAGCTCATAAGTGTGGGGTATGGGCAC ATAATGAAGNNGNGGGGGGGGCTTCTCATGAGGGGGTGGGGGGGGAAAAAACCCGCTTTT GGAGTCACAN |
Restriction Sites | Please inquire |
ACCN | NM_005314 |
Insert Size | 1700 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_005314.2, NP_005305.1 |
RefSeq Size | 2681 bp |
RefSeq ORF | 1155 bp |
Locus ID | 2925 |
UniProt ID | P30550 |
Protein Families | Druggable Genome, GPCR, Transmembrane |
Protein Pathways | Calcium signaling pathway, Neuroactive ligand-receptor interaction |
Gene Summary | Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. [provided by RefSeq, Jul 2008] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC210362 | GRPR (Myc-DDK-tagged)-Human gastrin-releasing peptide receptor (GRPR) |
CNY 3,656.00 |
|
RC210362L1 | Lenti ORF clone of Human gastrin-releasing peptide receptor (GRPR), Myc-DDK-tagged |
CNY 6,056.00 |
|
RC210362L2 | Lenti ORF clone of Human gastrin-releasing peptide receptor (GRPR), mGFP tagged |
CNY 5,890.00 |
|
RC210362L3 | Lenti ORF clone of Human gastrin-releasing peptide receptor (GRPR), Myc-DDK-tagged |
CNY 5,890.00 |
|
RC210362L4 | Lenti ORF clone of Human gastrin-releasing peptide receptor (GRPR), mGFP tagged |
CNY 5,890.00 |
|
RG210362 | GRPR (tGFP-tagged) - Human gastrin-releasing peptide receptor (GRPR) |
CNY 5,256.00 |