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Germinal Center Kinase (MAP4K2) (NM_004579) Human Untagged Clone
CAT＃: SC117289
MAP4K2 (untagged)-Human mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2)
CNY 6,016.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BL44; GCK; RAB8IP |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_004579 edited
CCCGGGATATCGTCGACCCACGCGTCCGCAGAGCCACGGGCGCCCGCCCCGCCCCGCGCC GCCCCGCGCCGGCTCCGCAGCTCGCGCCCGCCCGCCTGCCGGCCCGCCCGGCGCCGGGCC ATGGCGCTGCTGCGGGATGTGTCGCTGCAGGACCCGCGGGACCGCTTCGAGCTGCTGCAG CGCGTGGGGGCCGGGACCTATGGCGACGTCTACAAGGCCCGCGACACGGTCACGTCCGAA CTGGCCGCCGTGAAGATAGTCAAGCTAGACCCAGGGGACGACATCAGCTCCCTCCAGCAG GAAATCACCATCCTGCGTGAGTGCCGCCACCCCAATGTGGTGGCCTACATTGGCAGCTAC CTCAGGAATGACCGCTTGTGGATCTGCATGGAGTTCTGCGGAGGGGGCTCCCTGCAGGAG ATTTACCATGCCACTGGGCCCCTGGAGGAGCGGCAGATTGCCTACGTCTGCCGAGAGGCA CTGAAGGGGCTCCACCACCTGCATTCTCAGGGGAAGATCCACAGAGACATCAAGGGAGCC AACCTTCTCCTCACTCTCCAGGGAGATGTCAAACTGGCTGACTTTGGGGTGTCAGGCGAG CTGACAGCGTCTGTGGCCAAGAGGAGGTCTTTCATTGGGACTCCCTACTGGATGGCTCCC GAGGTGGCTGCTGTGGAGCGCAAAGGTGGCTACAATGAGCTATGTGACGTCTGGGCCCTG GGCATCACTGCCATTGAGCTGGGCGAGCTGCAGCCCCCTCTGTTCCACCTGCACCCCATG AGGGCCCTGATGCTCATGTCGAAGAGCAGCTTCCAGCCGCCCAAACTGAGAGATAAGACT CGCTGGACCCAGAATTTCCACCACTTTCTCAAACTGGCCCTGACCAAGAATCCTAAGAAG AGGCCGACAGCAGAGAAGCTCCTGCAGCACCCGTTCACGACTCAGCAGCTCCCTCGGGCC CTCCTCACACAGCTGCTGGACAAAGCCAGTGACCCTCATCTGGGGACCCCCTCCCCTGAG GACTGTGAGCTGGAGACCTATGACATGTTTCCAGACACCATTCACTCCCGGGGGCAGCAC GGCCCAGCCGAGAGGACCCCCTCGGAGATCCAGTTTCACCAGGTGAAATTTGGCGCCCCA CGCAGGAAGGAAACTGACCCACTGAATGAGCCGTGGGAGGAAGAGTGGACACTACTGGGA AAGGAAGAGTTGAGTGGGAGCCTGCTGCAGTCGGTCCAGGAGGCCCTGGAGGAAAGGAGT CTGACTATTCGGTCAGCCTCAGAATTCCAGGAGCTGGACTCCCCAGACGATACCATGGGA ACCATCAAGCGGGCCCCGTTCCTAGGGCCACTCCCCACTGACCCTCCAGCAGAGGAGCCT CTGTCCAGTCCCCCAGGCCCCAACAGCTCCCCACTGCTGCCCACGGCCTGGGCCACCATG AAGCAGCGGGAGGATCCTGAGAGGTCATCCTGCCACGGGCTCCCCCCAACTCCCAAGGTG CATATGGGCGCCTGCTTCTCCAAGGTCTTCAATGGCTGCCCCCTGCGGATCCACGCTGCT GTCACCTGGATTCACCCTGTTACTCGGGACCAGTTCCTGGTGGTAGGGGCCGAGGAAGGC ATCTACACACTCAACCTGCATGAACTGCATGAGGATACGCTGGAGAAGCTGATTTCACAT CGCTGCTCCTGGCTCTACTGCGTGAACAACGTGCTGCTGTCACTCTCAGGGAAATCCACG CACATCTGGGCCCATGACCTCCCAGGCCTGTTTGAGCAGCGGAGGCTACAGCAACAGGTT CCCCTCTCCATCCCCACCAACCGCCTCACCCAGCGCATCATCCCCAGGCGCTTTGCTCTG TCCACCAAGATTCCTGACACCAAAGGCTGCTTGCAGTGTCGTGTGGTGCGGAATCCCTAC ACGGGTGCCACCTTCCTGCTGGCCGCCCTGCCCACCAGCCTGCTCCTGCTGCAGTGGTAT GAGCCGCTGCAGAAGTTTCTGCTGCTGAAGAACTTCTCCAGCCCTCTGCCCAGCCCAGCT GGGATGCTGGAGCCGCTGGTGCTGGATGGGAAGGAGCTGCCGCAGGTGTGTGTTGGGGCC GAGGGGCCTGAGGGGCCCGGCTGCCGCGTCCTGTTCCATGTCCTGCCCCTGGAGGCTGGC CTGACGCCCGACATCCTCATCCCACCTGAGGGGATCCCAGGCTCGGCCCAGCAGGTGATC CAGGTGGACAGGGACACAATCCTAGTCAGCTTTGAACGCTGTGTGAGGATTGTCAACATG CAGGGCGAGCCCACGGCCACACTGGCACCTGAGCTGACCTTTGATTTCCCCATCGAGACT GTGGTGTGCCTGCAGGACAGTGTGCTGGCCTTCTGGAGCCATGGGATGCAAGGCCGAAGC CTGGATACCAATGAGGTGACCCAGGAGATCACAGATGAAACAAGGATCTTCCGAGTGCTT GGGGCCCACAGAGACATCATCCTGGAGAGCATTCCCACTGACAACCCAGAGGCGCACAGC AACCTCTACATCCTCACGGGCCACCAGAGCACCTACTAAGAGCAGCGGGCCTGTCCAGGG GCTCCCCGCCCCACCCCACGCCTTAGCTGCAGGCCCTTTTGGGCAAAGGGGCCCATCCTA GACCAGAGGAGCCCAGGCCCTGGCCCTGCTGGGGCTGAAGGTCAGAAGTAATCCTGAGAA ATGTTTCAGGCCTGGGGAGGGAGGGGAGCCCCCGACGCCTCTGCAATAACTGGACCAGGG GGAGCTGCTGTCACTCCCCCATCCCCG >OriGene 5' read for NM_004579 unedited
NGTCAGCATTTGTATACGACTCATATAGGGCGGCCGCGAATCCCGGGATATCGTCGACCC ACGCGTCCGCAGAGCCACGGGCGCCCGCCCCGCCCCGCGCCGCCCCGCGCCGGCTCCGCA GCTCGCGCCCGCCCGCCTGCCGGCCCGCCCGGCGCCGGGCCATGGCGCTGCTGCGGGATG TGTCGCTGCAGGACCCGCGGGACCGCTTCGAGCTGCTGCAGCGCGTGGGGGCCGGGACCT ATGGCGACGTCTACAAGGCCCGCGACACGGTCACGTCCGAACTGGCCGCCGTGAAGATAG TCAAGCTAGACCCAGGGGACGACATCAGCTCCCTCCAGCAGGAAATCACCATCCTGCGTG AGTGCCGCCACCCCAATGTGGTGGCCTACATTGGCAGCTACCTCAGGAATGACCGCTTGT GGATCTGCATGGAGTTCTGCGGAGGGGGCTCCCTGCAGGAGATTTACCATGCCACTGGGC CCCTGGAGGAGCGGCAGATTGCCTACGTCTGCCGAGAGGCACTGAAGGGGCTCCACCACC TGCATTCTCAGGGGAAGATCCACAGAGACATCAAGGGAGCCAACCTTCTCCTCACTCTCC AGGGAGATGTCAAACTGGCTGACTTTGGGGTGTCAGGCGAGCTGACAGCGTCTGTGGCCA AGAGGAGGTCTTTCATTGGGACTCCCTACTGGATGGCTCCCGAGGTGGCTGCTGTGGAGC GCAAAGGTGCTACAATGAGCTATGTGACGTCTGGGCCCTGNGCATCACTGCCATTGAGCT GGGCGAGCTGCAGCCCCCTCTGTTTCACCTGCACCCCATGAGGGCCCTGATGCTCATAGT CGAGAAGCAGTTNCCAGCCGCCCCAACTGAGAGATAAGACTCGCTGGACCCAGAATTTCA CCACTTTCTAAAACTGCCCCTGACCAGAATCTAAGAA |
| Restriction Sites | Please inquire |
| ACCN | NM_004579 |
| Insert Size | 3000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_004579.2, NP_004570.2 |
| RefSeq Size | 2964 bp |
| RefSeq ORF | 2463 bp |
| Locus ID | 5871 |
| UniProt ID | Q12851 |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | MAPK signaling pathway |
| Gene Summary | The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC217608 | MAP4K2 (Myc-DDK-tagged)-Human mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2) |
CNY 6,008.00 |
|
| RC217608L1 | Lenti ORF clone of Human mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2), Myc-DDK-tagged |
CNY 8,408.00 |
|
| RC217608L2 | Lenti ORF clone of Human mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2), mGFP tagged |
CNY 7,700.00 |
|
| RC217608L3 | Lenti ORF clone of Human mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2), Myc-DDK-tagged |
CNY 7,700.00 |
|
| RC217608L4 | Lenti ORF clone of Human mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2), mGFP tagged |
CNY 7,700.00 |
|
| RG217608 | MAP4K2 (tGFP-tagged) - Human mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2) |
CNY 7,608.00 |
|
| SC323630 | MAP4K2 (untagged)-Kinase deficient mutant (K45M) of Human mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2) |
CNY 6,016.00 |
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